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Acta Medica Iranica، جلد ۴۷، شماره ۴، صفحات ۳۲۵-۳۲۸
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عنوان انگلیسی Evaluation of Antimicrobial Susceptibility Patterns of Enterococci Isolated from Patients in Tehran University of Medical Sciences Teaching Hospitals
چکیده انگلیسی مقاله This study investigated the antibacterial resistance among enterococci isolated in Tehran hospitals. A total of 277 Enterococcus faecalis, 123 Enterococcus faecium and 13 isolates of other enterococcal strains were collected from 1 March 2002 to 15 April 2004 from three teaching hospitals of Tehran University of Medical Sciences. The minimum inhibitory concentrations (MIC) of tested antibiotics were determined by agar dilution method. Susceptible and resistant isolates were defined according to the species-related MIC breakpoints of the Clinical and Laboratory Standards Institute (CLSI) guidelines. Sixty- three percent of isolates were resistant to rifampicin (MIC90 64 µg/ml), 44% to ciprofloxacin (MIC90 16≤ µg/ml), 43% to erythromycin (MIC90 512 µg/ml), 32% to cefazolin (MIC90 256≤ µg/ml), 25% to penicillin (MIC90 32 µg/ml), 21% to ampicillin (MIC90 128≤ µg/ml), 8% to vancomycin (MIC90 ≤ 8 µg/ml), and 8% to teicoplanin (MIC90 16≤ µg/ml). All of the vancomycin-resistant strains carried the vanA phenotype and genotype. High level resistance to gentamicin and streptomycin were found in 52% and 83% of the isolates, respectively. The results indicated that a significant percentage of isolates are resistance to different antibiotics, pointing out the need for control strategies to avoid dissemination of resistant isolates and for continuous surveillance for the detection of emerging resistance traits.
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نویسندگان مقاله فرشته جبل عاملی | fereshteh jabalameli
department of microbiology, school of medicine, tehran university of medical sciences, tehran, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)

محمد ایمان عینی | mohammad emaneini
department of microbiology, school of medicine, tehran university of medical sciences, tehran, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)

شادی شاهسون | shadi shahsavan
department of microbiology, school of medicine, tehran university of medical sciences, tehran, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)

حسین صداقت | hossein sedaghat
department of microbiology, school of medicine, tehran university of medical sciences, tehran, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)

زهره abdolmaliki | zohreh abdolmaliki
department of veterinary pharmacology, faculty of veterinary medicine, university of tehran, tehran, iran.

سازمان اصلی تایید شده: دانشگاه تهران (Tehran university)

مرضیه علیقلی | marzieh aligholi
department of microbiology, school of medicine, tehran university of medical sciences, tehran, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)

نشانی اینترنتی http://acta.tums.ac.ir/index.php/acta/article/view/3600
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