این سایت در حال حاضر پشتیبانی نمی شود و امکان دارد داده های نشریات بروز نباشند
Acta Medica Iranica، جلد ۴۷، شماره ۳، صفحات ۱۹۷-۲۰۲
عنوان فارسی
چکیده فارسی مقاله
کلیدواژه‌های فارسی مقاله
عنوان انگلیسی Cerebral Vein Thrombosis:Screening of Acquired and Hereditary Thrombophilic Risk Factors
چکیده انگلیسی مقاله Cerebral vein thrombosis (CVT) is an infrequent condition with a large variety of causes that can lead to serious disabilities. However, in 20% to 35% of cases, no cause is found. In this study we evaluated the hereditary (P & C Proteins, antithrombin, mutation of prothrombin G20210A and factor V Leiden), other risk factors (hyperhomocycteinemia, factor VIII, ACL-ab, APL-ab, and OCP) and clinical manifestations among a population of Iranian patients with CVT. 18 women and 10 men aged 16 to 50 years with CVT were screened for inherited and acquired coagulation risk factors. No one had an abnormal ACL-ab, APL-ab or antithrombin III deficiency. One had prothrombin G20210A mutation (heterozygot) (3.6%). Hyperhomocycteinemia was observed in 5 patients (17.9%). APC-R was decreased in 3 (10.7%). 2 had positive factor V Leiden mutation (heterozygot) (7.1%). 17 had an increased of factor VIII (60.7). PS and PC deficiencies were each detected in two cases (7.1%). Conclusion: Our study suggests that screening for inherited thrombophilia may be an integral part in the diagnostic workup and duration of treatment in patients with CVT.
کلیدواژه‌های انگلیسی مقاله Cerebral vein thrombosis,thrombophilia,risk factors
نویسندگان مقاله پیام صراف | payam sarraf
department of neurology, imam khomeiny hospital, school of medicine, tehran university of medical sciences, tehran, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)

مجید غفارپور | majid ghaffarpoor
department of neurology, imam khomeiny hospital, school of medicine, tehran university of medical sciences, tehran, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)

حسین poormahmoodian | hosein poormahmoodian
department of neurology, imam khomeiny hospital, school of medicine, tehran university of medical sciences, tehran, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)

حسین harrirchian | hosein harrirchian
department of neurology, imam khomeiny hospital, school of medicine, tehran university of medical sciences, tehran, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)

حسن هاشمی | hasan hashemi
department of radiology, imam khomeiny hospital, school of medicine, tehran university of medical sciences, tehran, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)

نشانی اینترنتی http://acta.tums.ac.ir/index.php/acta/article/view/3575
فایل مقاله فایلی برای مقاله ذخیره نشده است
کد مقاله (doi)
زبان مقاله منتشر شده en
موضوعات مقاله منتشر شده
نوع مقاله منتشر شده Articles
برگشت به: صفحه اول پایگاه   |   نسخه مرتبط   |   نشریه مرتبط   |   فهرست نشریات