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Acta Medica Iranica، جلد ۴۷، شماره ۲، صفحات ۸۳-۸۸
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عنوان انگلیسی Prevalence of Dyslipidemia and Metabolic Abnormalities in HIV-Infected Patients
چکیده انگلیسی مقاله Dyslipidemia has become a common problem in human immunodeficiency virus (HIV) disease, especially in patients on combination antiretroviral therapy. We investigated the prevalence of and factors associated with dyslipidemia in HIV-infected patients in Iran. In this cross-sectional study, 190 HIV positive patients who referring to behavioral disease consulting centers (Shemiranat, Varamin) and Iranian Research Center for HIV/AIDS in Tehran, were studied from December 2005 to December 2006.A standardized questionnaire with epidemiological, clinical, and therapeutic data was completed by physicians. Blood samples were obtained for metabolic measurements. CD4 cell count was measured by flow cytometry. Levels of total cholesterol, triglycerides, and lactate were elevated in 16.9%, 29.9%, and 22.5% of patients, respectively. The prevalence of elevated triglyceride and cholesterol levels was significantly higher among patients receiving antiretroviral therapy than it was among those who were not receiving treatment. Fasting hyperglycemia was noted in 10.1% of patients overall, but this was not significantly associated with antiretroviral treatment group. Low HDL levels were noted in 52.4% of patients overall, and this finding did not vary by treatment group. There is a high prevalence of dyslipidemia in patients taking antiretroviral therapy in Iran. We conclude that the prevalence of and factors associated with metabolic abnormalities in HIV-infected Iranian patients are similar to those reported for Western and Asian studies.
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نویسندگان مقاله آمیتیس رمضانی | amitis ramezani
department of clinical research, pasteur institute of iran, tehran, iran. and infectious diseases research center, school of medicine, shaheed beheshti university of medical sciences, tehran, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی شهید بهشتی (Shahid beheshti university of medical sciences)

مینو محرز | minoo mohraz
iranian research center for hiv aids, tehran, iran.


داود یادگاری نیا | davood yadegarinia
infectious diseases research center, school of medicine, shaheed beheshti university of medical sciences, tehran, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی شهید بهشتی (Shahid beheshti university of medical sciences)

محمد بنی فضل | mohammad banifazl
iranian society for support patients with infectious disease, tehran, iran.


دکتر لطیف گچکار | latif gachkar
infectious diseases research center, school of medicine, shaheed beheshti university of medical sciences, tehran, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی شهید بهشتی (Shahid beheshti university of medical sciences)

سارا جمع | sara jam
iranian research center for hiv aids, tehran, iran.


آرزو آقاخانی | arezoo aghakhani
department of clinical research, pasteur institute of iran, tehran, iran.

سازمان اصلی تایید شده: انستیتو پاستور ایران (Pasteur institute of iran)

علی اسلامی فر | ali eslamifar
department of clinical research, pasteur institute of iran, tehran, iran.

سازمان اصلی تایید شده: انستیتو پاستور ایران (Pasteur institute of iran)

فرهاد یغمایی | farhad yaghmaie
health deputy of shaheed beheshti university of medical sciences, tehran, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی شهید بهشتی (Shahid beheshti university of medical sciences)

کامبیز نعمتی | kambiz nemati
north of tehran health center, shaheed beheshti university of medical sciences, tehran, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی شهید بهشتی (Shahid beheshti university of medical sciences)

علی اکبر ولایتی | ali akbar velayati
masih daneshvari hospital, shaheed beheshti university of medical sciences, tehran, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی شهید بهشتی (Shahid beheshti university of medical sciences)

نشانی اینترنتی http://acta.tums.ac.ir/index.php/acta/article/view/3551
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