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Acta Medica Iranica، جلد ۴۶، شماره ۵، صفحات ۴۱۳-۴۱۶
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عنوان انگلیسی ANTIMICROBIAL RESISTANCE OF SHIGELLA SPP. ISOLATED FROM DIARRHEAL PATIENTS IN ZAHEDAN
چکیده انگلیسی مقاله One of the great challenges in the treatment of infectious diseases is the resistance of pathogenic bacteria against antibiotics, and antibiotic resistance to Shigella is broadly observed in different parts of the world. The object of this study was to determine Shigella antibiotic resistance pattern against the antibiotics such as ampicillin, amoxicillin, trimethoprim-sulfamethoxazole, chloramphenicol, nalidixic acid, ciprofloxacin and ceftriaxone. In this cross-sectional study, a total of 147 Shigella strains were collected from the diarrheic patients referring to different medical centers of Zahedan. Specific antisera were used for serotyping of isolated Shigella and their antibiotic resistance patterns were determined by standard Kirby-Bauer method. Of the 147 studied Shigella strains, 102 (69.3%) belonged to S. flexneri , 32 (21.7 %) to S. dysenteriae , 11 (7.4%) to S. boydii , and 2 (1.36%) to S. sonnei species. The isolated strains showed resistance to ampicillin (99.3%), trimethoprim-sulfamethoxazole (52%) and nalidixic acid (1.3%), but there was no resistance against ciprofloxacin and ceftriaxone. According to the findings, it is suggested that antibiotics should not be used without laboratory testing (antibiogram).
کلیدواژه‌های انگلیسی مقاله Shigella, antimicrobial resistance, antibiotic, diarrhea
نویسندگان مقاله m qureishi | m qureishi
1 department of microbiology, school of medicine, zahedan university of medical sciences, zahedan,

سازمان اصلی تایید شده: دانشگاه علوم پزشکی زاهدان (Zahedan university of medical sciences)

a برجی | a borji
1 department of microbiology, school of medicine, zahedan university of medical sciences, zahedan,

سازمان اصلی تایید شده: دانشگاه علوم پزشکی زاهدان (Zahedan university of medical sciences)

m بکاییان | m bokaeian
1 department of microbiology, school of medicine, zahedan university of medical sciences, zahedan,

سازمان اصلی تایید شده: دانشگاه علوم پزشکی زاهدان (Zahedan university of medical sciences)

رودباری | m roudbari
2 department of statistics and mathematics, management and medical information school, iran univers


s شهرکی | s shahraki
1 department of microbiology, school of medicine, zahedan university of medical sciences, zahedan,

سازمان اصلی تایید شده: دانشگاه علوم پزشکی زاهدان (Zahedan university of medical sciences)

a نیازی | a niazi
3 department of pathology, school of medicine, zahedan university of medical sciences, zahedan, ira

سازمان اصلی تایید شده: دانشگاه علوم پزشکی زاهدان (Zahedan university of medical sciences)

m زنگی آبادی | m zangiabadi
1 department of microbiology, school of medicine, zahedan university of medical sciences, zahedan,

سازمان اصلی تایید شده: دانشگاه علوم پزشکی زاهدان (Zahedan university of medical sciences)

نشانی اینترنتی http://acta.tums.ac.ir/index.php/acta/article/view/3510
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