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Addiction and Health، جلد ۱۶، شماره ۱، صفحات ۱-۵
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عنوان انگلیسی Alcoholism and Socioeconomic Status among Patients with Hepatic Encephalopathy in Association with Increased Mortality
چکیده انگلیسی مقاله Background: Hepatic encephalopathy (HE) is a complex neuropsychiatric disorder indicated by a deterioration in the functioning 
of hepatocytes. Impaired brain function is observed in advanced alcoholic liver disease particularly manifesting as HE. The 
pathophysiology of alcohol-related HE remains unclear. Accordingly, this study aimed to assess alcoholism and socioeconomic 
status of patients with liver disease compared with stages of HE.
Methods: This cross-sectional study was conducted on 62 alcoholic patients who have been consuming alcohol for more than 
14 years. Patients were recruited based on the assessment of clinical symptoms and diagnosed according to the MELD and 
Child-Pugh scoring systems.
Findings: Descriptive statistics including demographic details and clinical features of patients were classified based on alcoholism 
and socioeconomic status. Patients belonging to the lower- and middle-income classes were more in number with a mean age 
of 46.66±10.21 and 47.14±6.36 years, respectively compared to upper-middle- and upper-income classes. The amount of 
alcohol intake was 116.59±45.60 in the middle class and 110.0±62.45 in the upper class. 
Conclusion: Increased progression of HE leads to a rise in the mortality rate due to higher consumption of alcohol. HE is a severe 
complication in alcohol-related liver cirrhosis that contributes to impaired cognitive function in patients. 
کلیدواژه‌های انگلیسی مقاله Keywords Alcoholism, Liver disease, Social class, Hepatic encephalopathy, mortality
نویسندگان مقاله Prabhudas Nelaturi |
Multidisciplinary Center for Biomedical Research, Aarupadai Veedu Medical College and Hospital, Vinayaka Mission’s Research Foundation (Deemed to be University), Kirumampakkam, Puducherry-607402, India

Sangeetha P Kademani |
Multidisciplinary Center for Biomedical Research, Aarupadai Veedu Medical College and Hospital, Vinayaka Mission’s Research Foundation (Deemed to be University), Kirumampakkam, Puducherry-607402, India

Ravikumar Sambandam |
Multidisciplinary Center for Biomedical Research, Aarupadai Veedu Medical College and Hospital, Vinayaka Mission’s Research Foundation (Deemed to be University), Kirumampakkam, Puducherry-607402, India

نشانی اینترنتی https://ahj.kmu.ac.ir/article_92468_8608e4eed6e5b7e64b0d5e8cba57dd32.pdf
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