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Veterinary Research Forum، جلد ۱۵، شماره ۵، صفحات ۲۱۹-۲۲۲
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عنوان انگلیسی Detection of antibodies against structural proteins of foot-and-mouth disease virus in bovines of western Uttar Pradesh, India
چکیده انگلیسی مقاله Foot-and-mouth disease (FMD) is considered as one of the most important contagious viral diseases affecting cloven-footed animals. For effective control of FMD, immunization along with herd immunity is essential in the field conditions. To assure and track the coverage and effectiveness of the vaccination program, the serological studies are very much required after the vaccination program. The present study was aimed to investigate the prevalence of antibodies against structural proteins of FMD virus (FMDV) serotypes of O, A and Asia-1 in seven districts of western Uttar Pradesh, India, and assure the efficacy of vaccination under National Animal Disease Control Program. A total of 308 sera samples were collected from apparent healthy vaccinated cattle and buffaloes from seven districts including Amroha, Baghpat, Bareilly, Bulandsahar, Gautam Budh Nagar, Meerut and Muzaffarnagar of western Uttar Pradesh, India. Determination of antibodies against structural proteins of FMDV was carried out using solid-phase blocking enzyme-linked immunosorbent assay. The protective level of the FMDV serotypes O, A and Asia-1 included in the inactivated trivalent vaccine was 66.55, 48.05 and 47.08% in bovines, respectively. To provide the higher level of protection against the circulating FMDV, the present study recommended the thorough investigation of the immunogenic interaction between the vaccine strains and the field strains. Further investigations should also be conducted with larger sample size and across diverse geographical regions to gain a more comprehensive understanding of herd immunity.
کلیدواژه‌های انگلیسی مقاله Foot-and-mouth disease virus,India,Solid-phase blocking ELISA,structural protein
نویسندگان مقاله Afroz Afroz |
Veterinary Officer, Animal Husbandry Department, District Mainpuri, India

Amit Kumar Verma |
Department of Veterinary Medicine, College of Veterinary and Animal Sciences, Sardar Vallabhbhai Patel University of Agriculture and Technology, Meerut , India

Amit Kumar |
Animal Biotechnology, College of Biotechnology, Sardar Vallabhbhai Patel University of Agriculture and Technology, Meerut, India

Surendra Upadhyay |
PhD Scholar, College of Biotechnology, Sardar Vallabhbhai Patel University of Agriculture and Technology, Meerut, India

Arbind Singh |
Livestock Farm Complex, College of Veterinary and Animal Sciences, Sardar Vallabhbhai Patel University of Agriculture and Technology, Meerut, India

نشانی اینترنتی https://vrf.iranjournals.ir/article_711950_afc5be5a4fb6f456d83512e0de548c4a.pdf
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