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Caspian Journal of Internal Medicine، جلد ۱۵، شماره ۳، صفحات ۳۸۲-۳۹۱
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عنوان انگلیسی Novel Biomarkers for the diagnosis of diabetic nephropathy
چکیده انگلیسی مقاله Diabetes mellitus and its complications are a known public health problem nowadays. Diabetic nephropathy is one of the main complications and the result of multiple mechanisms, including: activation of the renin-angiotensin-aldosterone system, formation of advanced glycation end products and chronic inflammation that led to glomerular and tubulo-interstitial damage producing mesangial expansion and glomerulosclerosis, which finally results in chronic kidney disease. Early detection of diabetic nephropathyis essential for adequate intervention to stop, or at least sloww down its progression. Multiple markers have been described, not only the classic ones such as serum creatinine, urea, and albuminuria, but at this point also novel biomarkers such as neutrophil gelatinase-associated lipocalin, tumor necrosis factor 1 receptor and monocyte chemoattractant protein-1, among others. The aim of this article was to provide an update review of the role of biomarkers in the diagnosis of diabetic nephropathy.
 
کلیدواژه‌های انگلیسی مقاله Diabetes mellitus, diabetic nephropathy, biomarkers, diagnosis
نویسندگان مقاله | Marcio Concepción-Zavaleta
Universidad Científica del Sur. Lima, Peru


| Juan Quiroz-Aldave
Division of Medicine, Hospital de Apoyo Chepén, Peru


| Jacsel Suarez Rojas
Division of Endocrinology. Santa Rosa Hospital, Southern Scientific University, Lima, Peru


| José Paz-Ibarra
Division of Endocrinology, Edgardo Rebagliati Martins National Hospital, Lima, Peru


| Pela Roseboom
Department of Medicine, Cesar Vallejo Mendoza Hospital, Santiago de Chuco, Peru


| Sofia Ildefonso-Najarro
Division of Endocrinology, Guillermo Almenara Irigoyen National Hospital, Lima, Peru


| Denis Cribilleros Zevallos
Division of Nephrology, National Center of Renal Heath, Lima, Peru


| Francisca Zavaleta-Gutiérrez
Division of Neonatology, Belén Hospital of Trujillo, Trujillo, Peru


| Julia Coronado-Arroyo
Department of Obstetrics and Gynecology, Edgardo Rebagliati Martins National Hospital, Lima, Peru


| Luis Concepción-Urteaga
Department of Medicine, Hospital Regional Docente of Trujillo, Trujillo, Peru
نشانی اینترنتی http://caspjim.com/browse.php?a_code=A-10-1924-2&slc_lang=en&sid=1
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کد مقاله (doi)
زبان مقاله منتشر شده en
موضوعات مقاله منتشر شده Nephrology
نوع مقاله منتشر شده Review Article
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