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Iranian Journal of Medical Physics، جلد ۳، شماره ۱، صفحات ۴۵-۵۴
عنوان فارسی
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عنوان انگلیسی Assessing the Efficiency of Ultrasound Parameters in the Detection of Bone Repair Process
چکیده انگلیسی مقاله Introduction: The low regeneration of bone in defective bones causes therapeutic problems. Various strategies to assess the healing of bone defects have been used which they include histological and histo-chemical analysis in an invasive study. The purpose of this study was to determine the ultrasonic parameters of bone as a promising noninvasive technology for assessing bone repair process. Materials and Methods: A total of twenty seven Newsland male rabbits being 4 month old were selected and a hole of 3 mm in diameter was bored in the mid region of their right tibia bone. After causing the injury to the right tibia the ultrasonic parameters including amplitude dependent speed of sound (AD-SOS) and bone radial thickness were measured on the injured tibia and the normal one (left tibia) at different time intervals (1, 8 and 15 day group). The bone transmission time (BTT) and ultrasonic bone profile index (UBPI) were estimated by AD-SOS which is calculated based on fast wave amplitude, signal dynamic and thickness. The rabbits in each group were sacrificed and histology study was performed on the injured tibia. Results: The results obtained from the histological sections in 1, 8 and 15 day post-injury, show ongoing normal healing process in the 8 and 15 day group. The bone repair was characterized by bone trabecular formation and osteoblast cell activity. The mean AD-SOS parameter for the 1, 8, 15 day and normal bone was 2265, 2203, 2176 and 1990 m/s, respectively, suggesting a non-invasive measurement to assess bone repair process. The measured result was in agreement which the histological analysis (p-value< 0.05 with ANOVA analysis). Discussion and Conclusion: The findings suggest that AD-SOS parameter might be suitable to assess the architectural quality of bone trabecular and repair process.
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نویسندگان مقاله m مختاری دیزجی | m mokhtari dizaji
associate professor, medical physics dept., tarbiat modarres university, tehran, iran.

سازمان اصلی تایید شده: دانشگاه تربیت مدرس (Tarbiat modares university)

a یوسفی دیبا | a yousefi diba
m. sc. in medical physics, medical physics dept., tarbiat modarres university, tehran, iran.

سازمان اصلی تایید شده: دانشگاه تربیت مدرس (Tarbiat modares university)

b لاریجانی | b. larijani
professor, metabolism and endocrine research center, tehran medical sciences university, tehran, iran.


m صالح نیا | m. salehnia
assistant professor, histology dept., tarbiat modarres university, tehran, iran.

سازمان اصلی تایید شده: دانشگاه تربیت مدرس (Tarbiat modares university)

g ترکمان | g. torkaman
associate professor, physical therapy dept., tarbiat modarres university, tehran, iran.

سازمان اصلی تایید شده: دانشگاه تربیت مدرس (Tarbiat modares university)

محمدرضا دادرس | m r dadras
m. sc. in medical physics, metabolism and endocrine research center, tarbiat modarres university, tehran, iran

سازمان اصلی تایید شده: دانشگاه تربیت مدرس (Tarbiat modares university)

نشانی اینترنتی http://ijmp.mums.ac.ir/article_8130.html
فایل مقاله اشکال در دسترسی به فایل - ./files/site1/rds_journals/145/article-145-314848.pdf
کد مقاله (doi)
زبان مقاله منتشر شده en
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نوع مقاله منتشر شده Original Paper
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