این سایت در حال حاضر پشتیبانی نمی شود و امکان دارد داده های نشریات بروز نباشند
Iranian Journal of Basic Medical Sciences، جلد ۲۷، شماره ۸، صفحات ۹۷۵-۹۸۴
عنوان فارسی
چکیده فارسی مقاله
کلیدواژه‌های فارسی مقاله
عنوان انگلیسی Evaluation of bioactive extract nanoparticles on pulp stem cell behavior relevant to dental care using chemical composition of gelatin-Arabian gum nano polymer
چکیده انگلیسی مقاله Objective(s): This study aimed to investigate the impact of bioactive plant extracts on the proliferation and migration of dental pulp stem cells (DPSCs) and their potential implications for dental care, focusing on the nurse-caring aspect. Materials and Methods: TDPSCs were cultured on gelatin polymer scaffolds mimicking the extracellular matrix (ECM) environment. Bioactive plant extracts with antibacterial, anti-inflammatory, and anti-oxidant properties were incorporated into the gelatin polymer at concentrations ranging from 0.1% to 2.0%. Proliferation and migration assays were performed, considering nurse-caring practices during the experiments.Results: Treatment with specific bioactive plant extracts significantly enhanced DPSC proliferation, showing a 2.5-fold increase compared to the control groups. The migration assay revealed a substantial increase in cell migration distance, with treated cells covering an average distance of 400-500 μm compared to 220-260 μm in the control group. Treated cells also exhibited improved viability and metabolic activity, with a 30% increase in cell viability and a 10-20% increase in metabolic activity compared to the control group. Conclusion: This study demonstrates that bioactive plant extracts have the potential to enhance DPSC proliferation, migration, viability, and metabolic activity. These findings support the use of these extracts in dental care, benefiting from the nurse-caring practices. 
کلیدواژه‌های انگلیسی مقاله Bioactive plant extracts, Chemical stability, Gelatin polymer scaffold, Migration, Pulp stem cells, Proliferation
نویسندگان مقاله | Xiaoni Tan
Department of Endodontics, Changsha Stomatological Hospital, No.389, Youyi Road, Tianxin District, Changsha 410008, Hunan Province, China


| Moli Zhang
Department of Endodontics, Changsha Stomatological Hospital, No.389, Youyi Road, Tianxin District, Changsha 410008, Hunan Province, China


| BiBo Tu
Department of Endodontics, Changsha Stomatological Hospital, No.389, Youyi Road, Tianxin District, Changsha 410008, Hunan Province, China
نشانی اینترنتی https://ijbms.mums.ac.ir/article_24116.html
فایل مقاله فایلی برای مقاله ذخیره نشده است
کد مقاله (doi)
زبان مقاله منتشر شده en
موضوعات مقاله منتشر شده
نوع مقاله منتشر شده Original Article
برگشت به: صفحه اول پایگاه   |   نسخه مرتبط   |   نشریه مرتبط   |   فهرست نشریات