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Iranian Journal of Public Health، جلد ۵۳، شماره ۶، صفحات ۱۳۶۱-۱۳۷۱
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عنوان انگلیسی Gender-Specific Differences in Prevalence and Association of Cardio-Metabolic Parameters and Hyperuricemia: A Population-Based Cross-Sectional Study, Nakhon Nayok, Thailand
چکیده انگلیسی مقاله Background: Although the prevalence of HUA is increasing, epidemiologic studies on HUA in the middle-aged and elderly population are limited. The present study aimed to calculate the prevalence and evaluate the sex-related associations between metabolic parameters and hyperuricemia (HUA) among middle-aged and elderly adults. Methods: This was a population-based cross-sectional study from 2018 to 2019 in rural areas of Nakhon Nayok Province, Thailand. We enrolled 780 subjects aged 40 yr and over for health check-ups and examination surveys. The age-standardized prevalence of HUA was estimated by the direct method. A multiple logistic regression was performed to identify the potential risk factors associated with HUA. Results: The prevalence of HUA were 30.9% (42% in males vs. 20% in females). Elderly adults were associated with a 35% increase in the risk of HUA. Obesity was found to be strongly associated with an increased prevalence of HUA in both sexes. Hypertriglyceridemia (51% increase in males vs. 23% increase in females), and high fasting glucose (90% increase in males vs. 49% increase in females) were also associated risk factors for HUA in both sexes. However, low high-density lipoprotein was only associated with a 67% increase in the risk of HUA in females. Conclusion: The age-standardized prevalence of HUA among females is relatively lower than in males. This study also revealed that obesity is strongly associated with HUA in both sexes.
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نویسندگان مقاله | Chawin Suwanchatchai
Department of Preventive and Community Medicine, Faculty of Medicine, Srinakharinwirot University, Nakhon Nayok 26120, Thailand


| Kitsarawut Khuancharee
Department of Preventive and Community Medicine, Faculty of Medicine, Srinakharinwirot University, Nakhon Nayok 26120, Thailand


| Chantra Tanunyutthawongse
Department of Biochemistry, Faculty of Medicine, Srinakharinwirot University, Bangkok 10110, Thailand


| Sivaporn Wannaiampikul
Department of Biochemistry, Faculty of Medicine, Srinakharinwirot University, Bangkok 10110, Thailand


| Photsathorn Haetanurak
Department of Physiology, Faculty of Medicine, Srinakharinwirot University, Bangkok 10110, Thailand
نشانی اینترنتی https://ijph.tums.ac.ir/index.php/ijph/article/view/32146
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