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Iranian Journal of Public Health، جلد ۵۳، شماره ۶، صفحات ۱۳۹۴-۱۴۰۳
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عنوان انگلیسی A Comparison between Serum 25-Hydroxyvitamin D3 Levels and Serum Ferritin in Children and Adolescents with Iron Deficiency Anemia, Thalassemia Minor, Thalassemia Major and Healthy People
چکیده انگلیسی مقاله Background: We aimed to determine the level of serum vitamin D and serum ferritin in four groups’ children and adolescents. Methods: This descriptive/analytical study was conducted in 2019 on children and adolescents with thalassemia aged 7-18 years in Ahvaz, Iran. Overall, 160 patients with the target inclusion and exclusion criteria were assigned into four groups (n=40) of people with thalassemia minor, thalassemia major, iron deficiency anemia and healthy individuals. The level of ferritin and vitamin D was assessed. Mann-Whitney test, Wilcoxon test and Spearman's correlation test were used as well as SPSS Statistics V21. Results: The mean age of the participants was 13.07 ± 3.82 yr and 100 people (62.5%) were male. In terms of vitamin D deficiency, 16 people (40%) had severe deficiency in iron deficiency group. The highest level of ferritin was found in thalassemia major group and the lowest in iron deficiency group. Regarding the level of vitamin D and ferritin in the healthy group, there was a statistically significant difference between mean vitamin D and serum ferritin levels (P=0.027). In iron deficiency group, this level of ferritin was observed with mild deficiency (P=0.017). In thalassemia major group, the increase in ferritin was associated with severe vitamin D deficiency (P=0.05. Conclusion: Severe vitamin D is seen in thalassemia major due to the increase in ferritin, but moderate deficiency of this vitamin in healthy people and mild deficiency in iron deficiency anemia group was observed considering the normal levels of ferritin.
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نویسندگان مقاله | Akram Hemmatipour
Department of Nursing, Abadan University of Medical Sciences, Abadan, Iran


| Bijan Kikhaei
Thalassemia and Hemoglobinopathy Research Center, Ahvaz Jundishapour University of Medical Sciences, Ahvaz, Iran


| Razieh Jalkani
Department of Hematology and Blood Banking, Faculty of Allied Medicine, Bushehr University of Medical Scince, Bushehr, Iran


| Mansour Ahmadnejad
Student Research Center of Shoushtar Faculty of Medical Sciences, Shoushtar, Iran


| Farhad Soleimanzadeh
Department of Nursing, Nursing Care Research Center in Chronic Diseases, School of Nursing and Midwifery, Ahvaz Jundishapour University of Medical Sciences, Ahvaz, Iran


| Dariush Rokhafrooz
Department of Nursing, Nursing Care Research Center in Chronic Diseases, School of Nursing and Midwifery, Ahvaz Jundishapour University of Medical Sciences, Ahvaz, Iran
نشانی اینترنتی https://ijph.tums.ac.ir/index.php/ijph/article/view/32024
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