این سایت در حال حاضر پشتیبانی نمی شود و امکان دارد داده های نشریات بروز نباشند
Iranian Journal of Basic Medical Sciences، جلد ۲۷، شماره ۹، صفحات ۱۰۸۵-۱۰۹۵
عنوان فارسی
چکیده فارسی مقاله
کلیدواژه‌های فارسی مقاله
عنوان انگلیسی Application of ferroptosis strategy to overcome tumor therapy resistance in breast and different cancer cells
چکیده انگلیسی مقاله This literature review emphasizes the innovative role of ferroptosis in cancer treatment. Ferroptosis is a kind of deliberate cell death that is characterized by the generation of lipid peroxides and needs the presence of iron. Ferroptosis is a controlled cell death process that adheres to certain rules and regulations. The inhibition of System Xc- and the involvement of GPX4 are two of the primary areas of exploration that are engaged in the process of ferroptosis. This review explores the treatments that are used to treat ferroptosis in a range of malignancies, with a particular focus on breast carcinoma. Attention is paid to certain pathways, such as the FSP1-independent regulation of glutathione, involvement of cholesterol, and the prominin 2-MVB/exosome-ferritin pathway. Ferroptosis plays a key role in resistance to tumor therapy.
کلیدواژه‌های انگلیسی مقاله Drug resistance, Ferroptosis, Glutathione peroxidase, Iron metabolism, Lipid metabolism, Neoplasms
نویسندگان مقاله | Waniya Shahid
Department of General Surgery Sub Specialty Breast Surgery, Shanxi First Medical Hospital affiliated to Shanxi Medical University, Yingze District, 030000, Taiyuan, China


| Ahmar Iqbal
Department of General Surgery Sub Specialty Breast Surgery, Shanxi First Medical Hospital affiliated to Shanxi Medical University, Yingze District, 030000, Taiyuan, China


| Iram Iqbal
Department of Pharmacology, Bahauddin Zakriya University Multan, Pakistan|Primary & Secondary Healthcare Department, Govt. of Punjab, Pakistan


| Arshad Mehmood
Department of Neurology, The Second Hospital of Hebei Medical University, Shijiazhuang 050000, Hebei, China


| Hongyan Jia
Department of General Surgery Sub Specialty Breast Surgery, Shanxi First Medical Hospital affiliated to Shanxi Medical University, Yingze District, 030000, Taiyuan, China
نشانی اینترنتی https://ijbms.mums.ac.ir/article_24465.html
فایل مقاله فایلی برای مقاله ذخیره نشده است
کد مقاله (doi)
زبان مقاله منتشر شده en
موضوعات مقاله منتشر شده
نوع مقاله منتشر شده Review Article
برگشت به: صفحه اول پایگاه   |   نسخه مرتبط   |   نشریه مرتبط   |   فهرست نشریات