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Iranian Journal of Blood and Cancer، جلد ۱۶، شماره ۲، صفحات ۳۴-۵۰
عنوان فارسی
چکیده فارسی مقاله
کلیدواژه‌های فارسی مقاله
عنوان انگلیسی Optimizing Patient Blood Management in Cardiac Surgery: A Systematic Review
چکیده انگلیسی مقاله
Background: Heart diseases are typically treated with cardiac surgery, which often requires preoperative, intraoperative, and postoperative blood transfusion. However, blood transfusion is a risk factor for serious complications after cardiac surgery, including death. Patient Blood Management (PBM) programs were developed to mitigate the risks of blood transfusion by reducing its use in cardiac surgery.
Objective: This systematic review aims to study the currently published literature on PBM strategies that effectively reduce the rates of preoperative, intraoperative, and postoperative blood transfusion for cardiac surgery.
Methodology: This systematic review analyzed preoperative blood management strategies in cardiac surgery, focusing on studies published between 2018 and 2024 designed to reduce blood transfusion rates. The study utilized a modified 2022 protocol for systematic reviews and meta-analysis, grading evidence using a 2008 system, and selected 21 studies for a systematic review.
Results: The studies identified 12 PBM strategies, including iron therapy, Aminocaproic acid, Cardiopulmonary by-pass system, cell salvage, Perfusion Blood Collection, gel foam patches, Large-volume acute normovolemic hemodilution, Platelets Transfusion Therapy, Modified Ultrafiltration, TEM-based algorithms, and restrictive management of SVO2, which significantly reduced blood transfusion volumes and rates before, during, and after cardiac surgery.
Conclusion: The 12 PBM strategies identified are valuable additions to the current list, but further clinical evaluation is needed to improve their efficacy and safety in cardiac surgery.
کلیدواژه‌های انگلیسی مقاله Blood transfusion, Cardiac surgery, Patient blood management, Systematic review, Bleeding disorder.
نویسندگان مقاله | Sultan Ghazzay Alotaibi
Cardiac Center, King Fahd Armed Forces Hospital, Ministry of Defense, Jeddah, Saudi Arabia.


| Muneeb Ammar Alnouri
Cardiac Center, King Fahd Armed Forces Hospital, Ministry of Defense, Jeddah, Saudi Arabia.


| Rawaa Mahmoud Sulaiman
Family Medicine Department, Dr. Sulaiman Fakeeh Hospital, Jeddah, Saudi Arabia


| Abdulkhalek Abduljaleel
King Fahad General Hospital, Jeddah, Saudi Arabia.


| Ahmed Foad Bogari
King Fahad General Hospital, Jeddah, Saudi Arabia.


| Hani Nabeel Mufti
King Faisal Cardiac Center, King Abdul-Aziz Medical City, Ministry of National Guard Health Affairs, Jeddah, Saudi Arabia
نشانی اینترنتی http://ijbc.ir/browse.php?a_code=A-10-1128-1&slc_lang=en&sid=1
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کد مقاله (doi)
زبان مقاله منتشر شده en
موضوعات مقاله منتشر شده Adults Hematology & Oncology
نوع مقاله منتشر شده مقاله مروری
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