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Iranian Journal of Basic Medical Sciences، جلد ۲۰، شماره ۲، صفحات ۱۱۰-۱۲۱

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عنوان انگلیسی Toxicology effects of saffron and its constituents: a review
چکیده انگلیسی مقاله Saffron (Crocus sativus L.) has been considered as a medicinal plant since ancient times and also widely used as food additive for its color, taste and odor. The pharmacological properties of saffron and its main constituents, crocin and safranal have been evaluated using different in vivo and in vitro models. Additionally, other lines of studies have found toxicological effects of saffron. However, a comprehensive review that covers all aspects of its toxicity has not been published yet. The current study provides classified information about the toxic effects of saffron and its constituents in various exposure conditions including acute, sub-acute, sub-chronic and chronic studies. Therapeutic doses of saffron exhibits no significant toxicity in both clinical and experimental investigations.
کلیدواژه‌های انگلیسی مقاله Crocetin, Crocin, Saffron, Safranal, Toxicity

نویسندگان مقاله حسن بدیع بستان | hasan badie bostan
department of pharmacodynamics and toxicology, school of pharmacy, mashhad university of medical sciences, mashhad, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی مشهد (Mashhad university of medical sciences)

صغری مهری | soghra mehri
department of pharmacodynamics and toxicology, school of pharmacy, mashhad university of medical sciences, mashhad, iran|pharmaceutical research center, mashhad university of medical sciences, mashhad, iran|neurocognitive research center, mashhad university of medical sciences, mashhad, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی مشهد (Mashhad university of medical sciences)

حسین حسین زاده | hossein hosseinzadeh
department of pharmacodynamics and toxicology, school of pharmacy, mashhad university of medical sciences, mashhad, iran|pharmaceutical research center, mashhad university of medical sciences, mashhad, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی مشهد (Mashhad university of medical sciences)


نشانی اینترنتی http://ijbms.mums.ac.ir/article_8230.html
فایل مقاله اشکال در دسترسی به فایل - ./files/site1/rds_journals/87/article-87-321236.pdf
کد مقاله (doi)
زبان مقاله منتشر شده en
موضوعات مقاله منتشر شده
نوع مقاله منتشر شده Review Article
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