| چکیده انگلیسی مقاله |
Dengue fever, an arboviral disease primarily transmitted by Aedes mosquitoes, poses a significant public health concern globally. Key vectors, such as Aedes aegypti, Aedes albopictus and Aedes cinereus, are widely distributed in tropical and subtropical regions, affecting over 140 countries. These species are also found in Iran, particularly in the southern, southeastern, and northern regions.
Diagnosing dengue fever presents challenges, including differentiating it from other febrile illnesses and recognizing early warning signs of severe dengue. Symptoms typically include acute fever, warning signs of severe illness, and potential complications. The clinical progression of dengue includes three phases: the febrile phase, critical phase, and recovery phase. A comprehensive understanding of clinical manifestations, prognostic indicators, diagnostic algorithms, and laboratory methods is crucial for accurate diagnosis, risk assessment, and effective disease management. Given the absence of specific antiviral treatments or vaccines for dengue, supportive care and symptomatic treatment remain essential.
This narrative review discusses the management of dengue fever, focusing on supportive care, fluid management, antipyretic and analgesic medications, and antiviral treatments. Additionally, it reviews potential future treatment strategies and emphasizes the importance of early diagnosis and prompt medical intervention in improving patient outcomes. The study also explores immunological targets, vaccine platforms, clinical trials, and future prospects for dengue vaccination. Furthermore, it presents prevention strategies targeting Aedes mosquitoes and outlines the challenges that lie ahead.
By adopting a comprehensive and interdisciplinary approach, we can pave the way for advancements in the prevention and control of dengue fever related to Aedes mosquito transmission. Continued research efforts, innovative collaborations, and public health training are vital to combat dengue fever and reduce its burden on affected populations worldwide. |
| نویسندگان مقاله |
سید رضا حسینی آرا | Reza Hosseiniara
Biochemistry and nutrition in Metabolic Diseases Research Center, Faculty of Medicine, Kashan University of Medical Sciences, Kashan, Iran
مرکز تحقیقات بیوشیمی و تغذیه در بیماریهای متابولیک، دانشکده پزشکی، دانشگاه علوم پزشکی کاشان، کاشان، ایران
وحید محمدی شاهرخی | Vahid Mohammadi-Shahrokhi
Department of Immunology, Faculty of Medicine, Rafsanjan University of Medical Sciences, Rafsanjan, Iran
دپارتمان ایمونولوژی، دانشکده پزشکی، دانشگاه علوم پزشکی رفسنجان، رفسنجان، ایران
صادق زارعی | Sadegh Zarei
Department of Biochemistry, Faculty of Medicine, Rafsanjan University of Medical Sciences, Rafsanjan, Iran
دپارتمان بیوشیمی، دانشکده پزشکی، دانشگاه علوم پزشکی رفسنجان، رفسنجان، ایران
روح الله دهقانی | Rouhullah Dehghani
Social Determinants of Health (SDH) Research Center, and Department of Environment Health, Kashan University of Medical Sciences, Kashan, Iran
مرکز تحقیقات عوامل اجتماعی موثر بر سلامت و گروه مهندسی بهداشت محیط، دانشگاه علوم پزشکی کاشان، کاشان، ایران
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