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Iranian Journal of Otorhinolaryngology، جلد ۳۶، شماره ۵، صفحات ۵۸۱-۵۸۶
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عنوان انگلیسی Submandibular Gland Preservation in Oral Cavity Squamous Cell Carcinomas Our Analysis at A Tertiary Care Hospital
چکیده انگلیسی مقاله Introduction:Surgical excision forms the principal treatment of oral cavity squamous cell carcinomas. The submandibular gland accounts for 70–90 % of unstimulated salivary volume. Its excision as a part of neck dissection has been found to cause high Incidence (21% vs 7%) of postoperative xerostomia. Recent studies have highlighted that the preservation of the SMG is possible and oncologically safe in early-grade OCSCC with N0 neck as the involvement of SMG in such cases is low and its preservation decreases the chances of xerostomia. Materials and Methods:80 subjects were included in the study to estimate the prevalence of metastatic submandibular gland involvement in oral cavity squamous cell carcinomas. The presence of metastasis into the salivary gland was studied and the mechanism/route of involvement was analysed. The comparison was made between the early and advanced tumors for SMG metastasis irrespective of the primary subsite involvement.Results:In the current study low prevalence (6.2 %) of metastasis to SMG was seen. It was seen in high-grade      tumors only. None of the early-grade tumors showed any evidence of SMG metastasis. The most common pattern (80%) of glandular involvement was a direct extension from the primary tumor. Conclusions:Our study concludes that SMG preservation neck dissections can be carried out in early-grade OCSCC irrespective of primary tumor site involvement. The advantages of preserving the SMG are multiple. Furthermore, the morbidity is markedly decreased with its preservation without any compromise on oncological safety.
کلیدواژه‌های انگلیسی مقاله Head and neck squamous cell carcinoma, Submandibular gland excision, Oral cavity tumors, Xerostomia, Neck dissection
نویسندگان مقاله | Shahid Rasool
Department of Ent- Head and Neck Surgery, Hamdard Institute of Medical Sciences, New Delhi, India.


| Ayushi Manghani
Department of Ent- Head and Neck Surgery, Hamdard Institute of Medical Sciences, New Delhi, India.


| Shilpam Sharma
Department of Ent- Head and Neck Surgery, Hamdard Institute of Medical Sciences, New Delhi, India.


| Zohda Tayyaba
Department of Ent- Head and Neck Surgery, Hamdard Institute of Medical Sciences, New Delhi, India.


| Sabina Khan
Department of Pathology, Hamdard Institute of Medical Sciences, New Delhi, India.


| Zarreen Parvez
Department of Ent- Head and Neck Surgery, Hamdard Institute of Medical Sciences, New Delhi, India.


| Neha Dhillon
Department of Ent- Head and Neck Surgery, Hamdard Institute of Medical Sciences, New Delhi, India.


| Khaja Naseeruddin
Department of Ent- Head and Neck Surgery, Hamdard Institute of Medical Sciences, New Delhi, India.


| Shamaaila Aftab
Department of Ent- Head and Neck Surgery, Hamdard Institute of Medical Sciences, New Delhi, India.


| Arsal Usman
Department of Ent- Head and Neck Surgery, Hamdard Institute of Medical Sciences, New Delhi, India.


| Hafsa Khan
Department of Ent- Head and Neck Surgery, Hamdard Institute of Medical Sciences, New Delhi, India.
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