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Dental Research Journal، جلد ۱۴، شماره ۱، صفحات ۰-۰
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عنوان انگلیسی Diagnostic accuracy of salivary creatinine, urea, and potassium levels to assess dialysis need in renal failure patients
چکیده انگلیسی مقاله Background: The prevalence of chronic renal failure is increasing because of increase in chronic debilitating diseases and progressing age of population. These patients experience accumulation of metabolic byproducts and electrolyte imbalance, which has harmful effects on their health. Timely hemodialysis at regular intervals is a life-saving procedure for these patients. Salivary diagnostics is increasingly used as an alternative to the traditional methods. Thus, the aim of the present study was to determine the diagnostic effi cacy of saliva in chronic renal failure patients. Materials and Methods: This case–control study included 82 individuals, of which 41 were chronic renal failure patients and 41 were age- and sex-matched controls. Blood and saliva were collected and centrifuged. Serum and supernatant saliva were used for biochemical analysis. Serum and salivary urea, creatinine, sodium, potassium, calcium, and phosphorus were evaluated and correlated in chronic renal failure patients using unpaired t-test, Pearson’s correlation coeffi cient, diagnostic validity tests, and receiver operative curve. Results: When compared to serum; salivary urea, creatinine, sodium, and potassium showed diagnostic accuracy of 93%, 91%, 73%, and 89%, respectively, based on the fi ndings of study. Conclusion: It can be concluded that salivary investigation is a dependable, noninvasive, noninfectious, simple, and quick method for screening the mineral and metabolite values of high-risk patients and monitoring the renal failure patients. Key Words: Creatinine, dialysis,Renal Insufficiency,saliva, serum, urea
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نویسندگان مقاله bhavana s bagalad | bhavana s bagalad


k p mohankumar | k p mohankumar


جی اس madhushankari | g s madhushankari


ماندانا donoghue | mandana donoghue


puneeth horatti kuberappa | puneeth horatti kuberappa


نشانی اینترنتی http://drj.mui.ac.ir/index.php/drj/article/view/1854
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زبان مقاله منتشر شده en
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