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Avicenna Journal of Phytomedicine، جلد ۷، شماره ۲، صفحات ۱۰۷-۱۱۵

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عنوان انگلیسی Cassia fistula: A remedy from Traditional Persian Medicine for treatment of cutaneous lesions of pemphigus vulgaris
چکیده انگلیسی مقاله Objective: Pemphigus is a rare autoimmune disease that may be fatal without proper medical intervention. It is a blistering disease that involves both the skin and mucus membranes, in which the most important causes of death comprise superimposed opportunistic infections and complications of long-term high-dose corticosteroid therapy or prolonged consumption of immune suppressant drugs. Skin lesions are the most important sources of infection, and any local treatment decreasing the healing time of lesions and reducing the total dosage of drugs is favorable. Materials and Methods: Here, we review the probable mechanism of action of a traditional formulary of Cassia fistula (C. fistula) fruit extract in almond oil as a new topical medication for reducing the duration of treatment of pemphigus vulgaris erosions. Result: C. fistula fruit oil has lupeol, anthraquinone compounds as rhein and flavonoids. Previous in vitro and animal studies on C. fistula fruit have demonstrated wound healing, antioxidative, anti-leukotrienes, anti-inflammatory, antibacterial and antifungal effects of this plant. Conclusion: It is hypothesized that C. fistula L. can be a botanical therapeutic choice for treatment of pemphigus erosions.
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نویسندگان مقاله فاطمه عطارزاده | fatemh atarzadeh
department of traditional iranian medicine, school of traditional medicine, tehran university of medical sciences, tehran, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)

امیر جلادت | amir jaladat
department of traditional persian medicine, school of medicine, shiraz, iran


لادن دستغیب | ladan dastgheib
molecular dermatology research center, department of dermatology, shiraz university of medical sciences, shiraz, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی شیراز (Shiraz university of medical sciences)

غلامرضا امین | gholamreza amin
department of traditional pharmacy, tehran university of medical sciences, tehran, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)

مجید نیمروزی | majid nimrouzi
department of traditional persian medicine, school of medicine, shiraz, iran


محمد کمالی نژاد | mohammad kamalinejad
department of pharmacognosy, school of pharmacy, shaheed beheshti university of medical sciences, tehran, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی شهید بهشتی (Shahid beheshti university of medical sciences)


نشانی اینترنتی http://ajp.mums.ac.ir/article_6629.html
فایل مقاله اشکال در دسترسی به فایل - ./files/site1/rds_journals/232/article-232-323384.pdf
کد مقاله (doi)
زبان مقاله منتشر شده en
موضوعات مقاله منتشر شده
نوع مقاله منتشر شده Mini Review Article
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