این سایت در حال حاضر پشتیبانی نمی شود و امکان دارد داده های نشریات بروز نباشند
Nanomedicine Journal، جلد ۴، شماره ۲، صفحات ۸۹-۹۷
عنوان فارسی
چکیده فارسی مقاله
کلیدواژه‌های فارسی مقاله
عنوان انگلیسی Effects of non-newtonian properties of blood flow on magnetic nanoparticle targeted drug delivery
چکیده انگلیسی مقاله Objective(s): One applications of nanotechnology is in the area of medicine which is called nanomedicine. Primary instruments in nanomedicine can help us to detect diseases and used for drug delivery to inaccessible areas of human tissues. An important issue in simulating the motion of nanoparticles is modeling blood flow as a Newtonian or non-Newtonian fluid. Sometimes blood flow is simulated as a Newtonian fluid but actually blood has nature of non-Newtonian fluid. Simulation of targeted drug delivery and motion of nanoparticles in the blood flow as Newtonian and non-Newtonian fluid flow is investigated in this paperMaterials and Methods: In this paper, the blood flow is modeled as both Newtonian and non-Newtonian fluid and the effects of each case on the motion of nanoparticles in blood flow and targeted drug delivery is investigated. The flow is modeled with finite volume method. The particle modeled with discrete phase model.Results: Cross, Herschel-Bulkley and Power-law models are used for simulating the non-Newtonian blood flow. Numerical simulations show that trajectory of nanoparticle’s movement and the required time to pass the vessel by blood flow is variable for different models. According to obtained results, non-Newtonian Power-law and Herschel-Bulkley models have closely similar results but they have significant differences compared with Newtonian model. Conclusion: According to the results, it is preferred in the simulation to model blood flow as a non-Newtonian fluid and uses one of Herschel- Bulkley or Power-law models. Otherwise the simulation is far different from real phenomena.
کلیدواژه‌های انگلیسی مقاله
نویسندگان مقاله مبین حقدل | mobin haghdel
department of fluid mechanics, shiraz university, shiraz, iran

سازمان اصلی تایید شده: دانشگاه شیراز (Shiraz university)

رضا کمالی | reza kamali
department of fluid mechanics, shiraz university, shiraz, iran

سازمان اصلی تایید شده: دانشگاه شیراز (Shiraz university)

علی حقدل | ali haghdel
department of electronics and communication engineering, shiraz university, shiraz, iran

سازمان اصلی تایید شده: دانشگاه شیراز (Shiraz university)

زهرا منصوری | zahra mansoori
department of physiology, shiraz university, shiraz, iran

سازمان اصلی تایید شده: دانشگاه شیراز (Shiraz university)

نشانی اینترنتی http://nmj.mums.ac.ir/article_8410.html
فایل مقاله اشکال در دسترسی به فایل - ./files/site1/rds_journals/295/article-295-325968.pdf
کد مقاله (doi)
زبان مقاله منتشر شده en
موضوعات مقاله منتشر شده
نوع مقاله منتشر شده مقاله پژوهشی
برگشت به: صفحه اول پایگاه   |   نسخه مرتبط   |   نشریه مرتبط   |   فهرست نشریات