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Addiction and Health، جلد ۱۶، شماره ۳، صفحات ۲۲۴-۲۲۷
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عنوان انگلیسی Naltrexone and its Effects on Craving and Alcohol Use among Patients with Alcohol Dependence Syndroms: A Report
چکیده انگلیسی مقاله Background: Naltrexone is a Food and Drug Administration (FDA)-approved anti-craving agent for the long-term treatment of 
alcohol dependence syndrome (ADS). However, it may not be equally effective in all patients. This study aims to assess naltrexone 
treatment response over four weeks in a national-level tertiary care setting.
Methods: Male patients with ADS (n=100) who were initiated on naltrexone were included in the study. The clinical data, 
including the drinking pattern and craving, were recorded at baseline. At the end of the one-month follow-up, the drinking status 
and compliance with naltrexone were recorded. 
Findings: At the end of one month, more than half of the patients (n=53) were retained in the study. All the treatment-retained 
patients (n=53) reported naltrexone consumption for more than 24 days in the last month. Those who retained in the study 
reported significantly less craving among 72% of patients, while an almost 50% reduction in alcohol use was observed.
Conclusion: This study adds to the evidence of outcomes with naltrexone in terms of reduced craving and alcohol use.
کلیدواژه‌های انگلیسی مقاله Alcohol dependence syndrome, Naltrexone, craving, alcohol use, Follow-up
نویسندگان مقاله Ram Kumar |
National Drug Dependence Treatment Centre, Department of Psychiatry, All India Institute of Medical Sciences, Delhi, India

Rizwana Quraishi |
National Drug Dependence Treatment Centre, Department of Psychiatry, All India Institute of Medical Sciences, Delhi, India

Siddharth Sarkar |
National Drug Dependence Treatment Centre, Department of Psychiatry, All India Institute of Medical Sciences, Delhi, India

Ravindra Rao |
National Drug Dependence Treatment Centre, Department of Psychiatry, All India Institute of Medical Sciences, Delhi, India

Atul Ambekar |
National Drug Dependence Treatment Centre, Department of Psychiatry, All India Institute of Medical Sciences, Delhi, India

نشانی اینترنتی https://ahj.kmu.ac.ir/article_92509_cfc4bfe2a87b53c54ae0b273ca05331e.pdf
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