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Iranian Journal of Medical Physics، جلد ۱۳، شماره ۴، صفحات ۲۲۸-۲۳۵
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عنوان انگلیسی Comparison of Two Quantitative Susceptibility Mapping Measurement Methods Used For Anatomical Localization of the Iron-Incorporated Deep Brain Nuclei
چکیده انگلیسی مقاله Introduction Quantitative susceptibility mapping (QSM) is a new contrast mechanism in magnetic resonance imaging (MRI). The images produced by the QSM enable researchers and clinicians to easily localize specific structures of the brain, such as deep brain nuclei. These nuclei are targets in many clinical applications and therefore their easy localization is a must. In this study, we aimed to implement two QSM estimation algorithms, threshold-based k-space division (TKD) and morphology enabled dipole inversion (MEDI) in presurgical planning. Materials and Methods In this study, susceptibility weighted imaging (SWI) was performed on six patients referred to our center for presurgical planning purposes. The susceptibility values, as well as the contrast-to-noise ratio of few brain regions were estimated. To identify the algorithm, which was best applicable to clinics, a comparison of the two methods was performed. Results QSM images were produced; however, the results did not show any significant differences between the susceptibility values of the two methods. The contrast-to-noise ratio for the susceptibility values of the subthalamic nucleus and substantia nigra brain regions were significantly superior using the MEDI approach over TKD, suggesting improved localization of brain regions using the former method. Conclusion This study suggests that to identify specific brain regions, such as deep brain nuclei, a QSM contrast would be more beneficial than the conventional MRI contrasts. This study compared MEDI and TKD methods for quantification of brain susceptibility maps, and results showed that the MEDI method resulted in higher-quality images.
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نویسندگان مقاله حدیث الوانکار golpaygan | hadis alvankar golpaygan
neuro imaging and analysis group niag , research center for molecular and cellular imaging rcmci , tehran university of medical sciences, tehran, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)

محمد علی عقابیان | mohammad ali oghabian
neuro imaging and analysis group niag , research center for molecular and cellular imaging rcmci , tehran university of medical sciences, tehran, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)

سید امیر حسین بتولی | seyed amir hossein batouli
neuro imaging and analysis group niag , research center for molecular and cellular imaging rcmci , tehran university of medical sciences, tehran, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)

آرش زارع صادقی | arash zare sadeghi
department of medical physics and biomedical engineering, faculty of medicine, tehran university of medical science, tehran, iran

سازمان اصلی تایید شده: دانشگاه تهران (Tehran university)

نشانی اینترنتی http://ijmp.mums.ac.ir/article_8295.html
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زبان مقاله منتشر شده en
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نوع مقاله منتشر شده Original Paper
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