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گوارش، جلد ۲۹، شماره ۲، صفحات ۱۲۰-۱۲۳
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چکیده فارسی مقاله
کلیدواژه‌های فارسی مقاله
عنوان انگلیسی A Case Report of Primary Biliary Cholangitis Related to Hepatitis in a 7-Year-Old Girl from Iran
چکیده انگلیسی مقاله Primary biliary cholangitis (PBC), formerly known as primary biliary cirrhosis, is a liver disease . This is a chronic autoimmune disease, which can worsen over time and recur periodically. If left untreated, biliary cirrhosis may lead to liver failure. Considering that PBC is a rare disease in all age groups, especially in children, the purpose of this report was to describe a girl with hepatitis A  virus (HAV) who was then diagnosed with PBC. This child is the first case reported in Iran. The patient is a 7-year-old girl with a pale complexion and eyes with a yellowish cross who was referred to the doctor. Considering that this patient had hepatitis, a blood test was requested to check the level of cholesterol and liver enzymes. The absence of cholestatic liver enzymes was observed in tests. Then, an anti-mitochondrial (AMA) test was requested for the patient, the result of which was negative. Finally, with imaging and biopsy, the diagnosis of PBC was confirmed for the patient. After the definite diagnosis of the disease, the child was treated with ursodeoxycholic acid (UDCA). The child in question is suffering from two medical and immunological diseases, HAV and PBC. Since this child was first infected with HAV, it is possible that the cause of PBC was HAV.
کلیدواژه‌های انگلیسی مقاله Primary biliary cholangitis, Hepatitis, Biliary cirrhosis
نویسندگان مقاله | Mahmood Haghighat
Gastroenterohepatology Research Center, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran


| Seyed Mohsen Dehghani
Gastroenterohepatology Research Center, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran


| Maryam Ataollahi
Distinguished Professor of Pediatrics Gastroenterology, Department of Pediatrics, School of Medicine, Namazi Teaching Hospital, Abu Ali Sina for Medicine & Organ Transplant, Shiraz University of Medical Sciences


| Mohammad Hadi Imanieh
Professor of Molecular Pathology & Cytogenetics, Department of Pathology, School of Medicine, Shiraz Transplant Research Center, Stem Cells Research Institute, Abu Ali Sina for Medicine & Organ Transplant, Shiraz University of Medical Sciences, Shiraz, Iran


| Bita Geramizadeh
Gastroenterohepatology Research Center, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran


| Iraj Shahramian
Pediatric Gastroenterology and Hepatology Research Center, Zabol University of Medical Sciences, Zabol, Iran


| Mahdie Arefi
Pediatric Gastroenterology and Hepatology Research Center, Zabol University of Medical Sciences, Zabol, Iran


| Masoud Tahani


نشانی اینترنتی http://govaresh.org/index.php/dd/article/view/2640
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نوع مقاله منتشر شده Case Report
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