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Physiology and Pharmacology، جلد ۲۱، شماره ۱، صفحات ۶۳-۷۱

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عنوان انگلیسی Effects of Nymphaea lotus Linn. (Nymphaeaceae) extract on sperm quality and reproductive function of adult albino male rats
چکیده انگلیسی مقاله Introduction: Nymphea lotus Linn (N. lotus) flowers are used empirically for the treatment of male sexual disorders in Cameroon west region. This study was aimed to evaluate the effects of the N. lotus on some parameters of male fertility in adult albino male rats. Methods: twenty four male rats were divided in 4 groups (n=6 each) and subjected to the following treatment: distilled water as vehicle control (10 ml/kg), testosterone as reference drug (5 mg/kg) and N. lotus flowers aqueous extract at the doses of 75 (NL75) and 150 mg/kg (NL150). Distilled water and aqueous extract of the plant were given once daily whereas testosterone was injected intramuscularly once a week. Treatment lasted for 55 days. Index of libido, sperm count, motility and viability were assessed. Relative weight and histology of some androgens dependent organs were analyzed. Results: Our results showed the treatment with NL75 during 55 days, increased markedly the index of libido (83.33%) in animals compared to control (50%). Both N. lotus treated groups showed a significant elevation (P< 0.05) of the sperm count compared to testosterone treated animals. NL75 and NL150 also induced a significant increase of the sperm motility (P< 0.001; P< 0.01). NL75 induced a considerable increase in sperm viability (66.35% vs. 50.11%) compared to control. Further, NL75 also improved significantly the relative weight of testis (P< 0.05), prostate (P< 0.001) and penis (P< 0.05) compared to control, suggesting anabolic effects of our plant. Conclusion: From these findings, it was concluded that N. lotus flowers have androgenic and reproductive properties justifying its empirical uses.
کلیدواژه‌های انگلیسی مقاله Plants, Androgens, Testis, Fertility, Male rats

نویسندگان مقاله kameni poumeni mireille | kameni poumeni mireille
laboratory of animal physiology, department of animal biology and physiology, faculty of science, university of yaounde i, yaounde, cameroon


dzeufiet djomeni پاوول desire | dzeufiet djomeni paul desire
laboratory of animal physiology, department of animal biology and physiology, faculty of science, university of yaounde i, yaounde, cameroon


bilanda danielle claude | bilanda danielle claude
laboratory of animal physiology, department of animal biology and physiology, faculty of science, university of yaounde i, yaounde, cameroon


mengue ngadena yolande sandrine | mengue ngadena yolande sandrine
laboratory of animal physiology, department of animal biology and physiology, faculty of science, university of yaounde i, yaounde, cameroon


ngoungouré madeleine شنتال | ngoungouré madeleine chantal
laboratory of animal physiology, department of animal biology and physiology, faculty of science, university of yaounde i, yaounde, cameroon


mballa marguerite francine | mballa marguerite francine
laboratory of animal physiology, department of animal biology and physiology, faculty of science, university of yaounde i, yaounde, cameroon


mbolang nguegan lohik | mbolang nguegan lohik
laboratory of animal physiology, department of animal biology and physiology, faculty of science, university of yaounde i, yaounde, cameroon


dimo theophile | dimo theophile
laboratory of animal physiology, department of animal biology and physiology, faculty of science, university of yaounde i, yaounde, cameroon


kamtchouing پییر | kamtchouing pierre
laboratory of animal physiology, department of animal biology and physiology, faculty of science, university of yaounde i, yaounde, cameroon



نشانی اینترنتی http://phypha.ir/ppj/browse.php?a_code=A-10-935-1&slc_lang=fa&sid=en
فایل مقاله اشکال در دسترسی به فایل - ./files/site1/rds_journals/26/article-26-327728.pdf
کد مقاله (doi)
زبان مقاله منتشر شده en
موضوعات مقاله منتشر شده Endocrinology
نوع مقاله منتشر شده Original Research
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