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Iranian Journal of Medical Physics، جلد ۲۱، شماره ۴، صفحات ۲۴۹-۲۵۷
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عنوان انگلیسی Study of the Radio-Protective Effects of Henna Mixed With Vinegar on the Skin of Irradiated Rats
چکیده انگلیسی مقاله Introduction: Skin damage is one of the most common challenges of radiation therapy. In the present study an attempt was made to evaluate the radio-protective effects of henna mixed with vinegar on the skin. Material and Methods: The rats were divided into Control (no treatment), R (receiving radiation alone), V (receiving vinegar alone), H (receiving henna mixed with vinegar), R + H (receiving henna mixed with vinegar and then radiation), and R + V (receiving vinegar and then radiation) groups. All rats were euthanized and their skins’ pathological damage and the level of super oxide dismutase (SOD) and Mallon dialdehyde (MDA) were evaluated. The rats were irradiated with 15 Gy (6MV) X-rays. Results: Increase MDA and decrease SOD were seen in R group. However, these changes were ameliorated in R + H group, although the difference was not significant. Vinegar significantly decreased MDA induced by radiation, but could not increase the SOD level. The rate of skin pathological damage in R group were higher than in Control. However, the level of these lesions was lower in R + H and R + V groups compared to R group. The rate of dermatitis and sweat gland atrophy in R + H and R + V groups were less than R group and similar to the level in the control group. Conclusion: Henna and vinegar could reduce the skin injuries induced by radiation. Regarding pathological injuries, the effects of vinegar alone was more than henna, but regarding antioxidant activity, the protective effect of henna mixed with vinegar was better than vinegar alone.
کلیدواژه‌های انگلیسی مقاله Radiation Protection, Henna, Skin, Grape vinegar, Radiotherapy
نویسندگان مقاله | Mojgan Hasanzade
Department of Medical Physics, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.


| Mohammad Taghi Bahreyni Toossi
Medical Physics Department, Medical Physics Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.


| Masoumeh Gharib
Department of Pathology, Mashhad University of Medical Sciences, Mashhad, Iran.


| Shirin Taraz Jamshidi
Kidney Transplantation Complications Research Center, Mashhad University of Medical Sciences, Mashhad, I.R. Iran.


| Hamid Gholamhosseinian
Medical Physics Dept, Faculty of Medicine, Mashhad University of Medical Sciences


| Shokouhozaman Soleymanifard
Associate Professor of Medical Physics, Research Center of Medical Physics, Mashhad University of Medical Sciences, Mashhad, Iran
نشانی اینترنتی https://ijmp.mums.ac.ir/article_25064.html
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زبان مقاله منتشر شده en
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نوع مقاله منتشر شده Original Paper
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