| چکیده انگلیسی مقاله |
Background: Considering the high prevalence and clinical importance of herpes simplex virus (HSV) infection worldwide, we aimed to evaluate the seroprevalence of HSV-1 and HSV-2 in a population aged between 15 and 35 years in Mashhad, Iran.
Methods: This cross-sectional study was conducted on 916 cases composed of 288 (31.4%) men and 628 (68.6%) women. Using ELISA method, the presence of IgM and IgG antibodies against HSV-1 and HSV-2 was assessed.
Results: Among the population studied, 681 (74.3%) cases were positive for anti-HSV antibodies, while 235 (25.7%) cases were negative. Moreover, no IgMs were found and all positive subjects had IgG antibodies. Age (p < 0.001), occupation (p < 0.001), education (p = 0.006), smoking (p = 0.029), and BMI (p = 0.004) demonstrated a significant association with HSV-1 and HSV-2 infection.
Conclusion: Our study indicates a high seroprevalence of HSV infection; however, there was no cases positive for IgM antibodies, suggesting the high prevalence of latent infection.
|
| نویسندگان مقاله |
| Ahmad Taherpoor
Department of Microbiology and Virology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran
| Arastoo Vojdani
Department of Microbiology and Virology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran
| Seyed Mohamad Ali Hashemi
Student Research Committee, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran
| Arian Amali
Student Research Committee, Paramedical Department, Mashhad Medical Sciences Branch, Islamic Azad University, Mashhad, Iran
| Mohammad Reza Mardani
Department of Microbiology and Virology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran
| Majid Ghayour Mobarhan
International UNESCO Center for Health-Related Basic Sciences and Human Nutrition, Department of Nutrition, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran
| Habibollah Esmaily
Social Determinants of Health Research Center, Mashhad University of Medical Sciences, Mashhad, Iran
| MohammadTaghi Shakeri
Social Determinants of Health Research Center, Mashhad University of Medical Sciences, Mashhad, Iran
| Mansoureh Bakhshi
Antimicrobial Resistance Research Center, Mashhad University of Medical Sciences, Mashhad, Iran
| Mojtaba Meshkat
Department of Community Medicine, Faculty of Medicine, Mashhad Medical Sciences, Islamic Azad University, Mashhad, Iran
| Amin Hooshyar Chechaklou
Antimicrobial Resistance Research Center, Mashhad University of Medical Sciences, Mashhad, Iran
| Samaneh Abolbashari
Antimicrobial Resistance Research Center, Mashhad University of Medical Sciences, Mashhad, Iran
| Aida Gholoubi
Metabolic Syndrome Research Center and Medical Genetics Research Center, Mashhad University of Medical Sciences, Mashhad, Iran
| Zahra Meshkat
Antimicrobial Resistance Research Center, Mashhad University of Medical Sciences, Mashhad, Iran
|