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Journal of Medical Microbiology and Infectious Diseases، جلد ۱۲، شماره ۲، صفحات ۸۴-۹۹

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عنوان انگلیسی Mucormycosis: An Emerging Fungal Infection in the COVID-19 Pandemic
چکیده انگلیسی مقاله During the COVID-19 pandemic, there has been a resurgence of mucormycosis, a rare and opportunistic fungal infection, with India reporting a particularly notable increase in incidence. Mucormycosis is a life-threatening condition that requires prompt diagnosis and treatment to prevent high mortality rates and severe sequelae. It is caused by the inhalation of spores from ubiquitous filamentous fungi belonging to the order Mucorales. Individuals with compromised immune systems or underlying conditions, such as diabetes, ketoacidosis, and neutropenia, are particularly vulnerable to infection. The risk and severity of mucormycosis are exacerbated by several factors, including corticosteroid therapy, prolonged intensive care stay, and the use of ventilators. Additionally, contaminated oxygen humidifiers pose a significant risk. Effective management of mucormycosis in critically ill COVID-19 patients relies on early diagnosis, optimization of predisposing factors, timely antifungal treatment, surgical debridement, and adjuvant therapies. Imaging modalities such as contrast-enhanced CT scans and MRI are crucial for guiding surgical debridement and assessing disease extent. This review article provides a comprehensive overview of the clinical pathogenesis, risk factors, diagnosis, treatment, and challenges associated with mucormycosis in COVID-19 patients, summarizing the latest findings in this field.


 
کلیدواژه‌های انگلیسی مقاله COVID-19 infections, Mucormycetes, Organ damage, Risk factors and linkages

نویسندگان مقاله | Parisa Saberi-Hasanabadi
Ph.D in Toxicology and pharmacology, Faculty of pharmacy, Mazandaran University of Medical Sciences, Sari, Iran; Student Research Committee, Mazandaran University of Medical sciences, sari, Iran


| Milad Esmaeilzadeh Farmad
9th Dey of Torbat Heydariyeh Hospital, Mashhad University of Medical Sciences, Mashhad, Iran


| Ramin Ataee
Medicinal Plants Research Center, Mazandaran University of Medical Sciences, Sari, Iran



نشانی اینترنتی http://jommid.pasteur.ac.ir/browse.php?a_code=A-10-489-1&slc_lang=en&sid=1
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کد مقاله (doi)
زبان مقاله منتشر شده en
موضوعات مقاله منتشر شده Infectious diseases and public health
نوع مقاله منتشر شده Review article
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