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Journal of Medical Microbiology and Infectious Diseases، جلد ۱۱، شماره ۳، صفحات ۱۴۱-۱۴۷
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چکیده فارسی مقاله
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عنوان انگلیسی Phenotypic Detection of Extended-Spectrum β-lactamases (ESBLs) and Aminopenicillin Cephalosporinase (AmpC)-Producing Bacterial Isolates from Surfaces of Hospital Fomites and Hands of Healthcare Workers
چکیده انگلیسی مقاله Introduction: The hospital environment can significantly contribute to the spreading of bacterial isolates that pose a risk to public health. In this study, we analyzed bacteria found on hospital fomites and the hands of healthcare workers to determine the presence of resistant enzymes such as ESBLs and AmpC. Methods: We studied 100 samples collected from hospital fomites - including the hands of healthcare workers - for bacterial growth, which were subsequently identified using standard procedures. Standard disk methods were used to screen Gram-negative bacteria (GNB) for ESBL and AmpC production, including presumptive and confirmatory testing. Results: 46 (46.0%) Gram-negative bacteria were isolated from all sampling sites, including a preponderance of Pseudomonas aeruginosa and Escherichia coli. Of the 46 GNBs, 31 (67.4%) and 27 (58.7%) were resistant to ceftazidime and ceftriaxone, respectively. The double disk synergy test (DDST) showed ESBL in 34 (73.1%) of the isolates, with the highest prevalence in E. coli (32.3%) and P. aeruginosa (26.5%). These isolates were primarily associated with patients’ bedding (32.4%), tablets (26.5%), and sinks (20.6%), although there was no statistical difference (P=0.998). Presumptive AmpC production was 100% in isolates of K. pneumoniae, C. diversus, Shigella spp., and S. marcescens but variable in other isolates. The combined disk test (CDT) showed that 29 (63.0%) isolates were AmpC-producing GNB, with the highest prevalence in E. coli (34.5%). Conclusion: The isolation of bacteria with these types of resistance from the surfaces of hospital fomites may negatively impact the quality of healthcare delivery.
کلیدواژه‌های انگلیسی مقاله Hospital, Fomites, Healthcare workers, Bacteria, Resistance, Phenotype
نویسندگان مقاله | Musa Y. Tula
Department of Biological Science Technology, Federal Polytechnic Mubi, Adamawa State, Nigeria


| Osaretin Iyoha
Department of Medical Microbiology, School of Medicine, College of Medical Sciences, University of Benin, P.M.B. 1152, Benin City, Nigeria


| Richard Elisha
Department of Pharmaceutical and Biomedical Technology, Federal Polytechnic Mubi, Adamawa State, Nigeria


| Joel Filgona
Department of Microbiology, Adamawa State University Mubi, Nigeria


| Abumhere S. Aziegbemhin
Department of Microbiology, Faculty of Life Sciences, University of Benin, PMB 1154 Ugbowo, Benin City, Edo State Nigeria
نشانی اینترنتی http://jommid.pasteur.ac.ir/browse.php?a_code=A-10-450-1&slc_lang=en&sid=1
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کد مقاله (doi)
زبان مقاله منتشر شده en
موضوعات مقاله منتشر شده Anti-microbial agents, resistance and treatment protocols
نوع مقاله منتشر شده Original article
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