این سایت در حال حاضر پشتیبانی نمی شود و امکان دارد داده های نشریات بروز نباشند
فصلنامه علمی پژوهشی گیاهان دارویی، جلد ۱، شماره ۳۳، صفحات ۷۵-۸۰
عنوان فارسی
چکیده فارسی مقاله
کلیدواژه‌های فارسی مقاله
عنوان انگلیسی Treatment Effects of Ginger Rhizome & Extract of Carrot seed on Diabetic Nephropathy in Rat
چکیده انگلیسی مقاله Background: Antioxidants have essential effect on tissue regeneration after cells injury. Enhanced oxidative stress and changes in antioxidant capacity are considered to play an important role in the pathogenesis of chronic diabetes mellitus. Ginger rhizome and carrot seed are strong antioxidants and long-term treatment of Streptozotocin induced–diabetic animals with these herbs, has been shown to reduce oxidative stress. Objective: Evaluation to treatment effect of Ginger rhizome and extract of carrot seed on nephropathy after diabetes inducement. Methods: Wistar male rat (n=70) were allocated into seven groups, control group, carrot seed extract group, ginger group, control- Diabetic group received 55mg/kg (IP) streptozotocin (STZ), treatment diabetic group that received carrot seed extract, treatment diabetic group that received ginger and treatment diabetic group that received carrot seed extract plus ginger. Animals were kept in standard condition. In 30 day after inducing diabetes, 5ml blood were collected for analyzing of TAC and MDA levels, and kidney tissues of Rats were removed in all groups then prepared for analysis. Results: Pathological changes in diabetic group which received carrot seed and ginger together was decreased compared to control group. The rate of serum TAC significantly increased in diabetic groups which received carrot seed and ginger together significantly in comparison to control-diabetic group (p< 0.05). Conclusion: Since in our study 25 mg/kg carrot seed extract and 100 mg/kg ginger have prevented kidney tissue injury by reducing level of Reactive Oxygen Species (ROS) in serum, so it seems that using it can be effective for treatment nephropathy in Diabetic rats.
کلیدواژه‌های انگلیسی مقاله Carrot seed, Ginger, Nephropathy, Diabetic Rats
نویسندگان مقاله aa خاکی | aa khaki
department of anatomical sciences, islamic azad university, bonab branch, bonab

سازمان اصلی تایید شده: دانشگاه آزاد اسلامی علوم و تحقیقات (Islamic azad university science and research branch)

a خاکی | a khaki
department of veterinary pathology, islamic azad university, tabriz branch, iran, 1 etekali la, south shariati street, tabriz, iran, mobile phone 98-9143138-399

سازمان اصلی تایید شده: دانشگاه آزاد اسلامی علوم و تحقیقات (Islamic azad university science and research branch)

hr احمدی آشتیانی | hr ahmadi ashtiani
clinical biochemistry, tarbiat-e-modarres university, school of medical science, department of clinical biochemistry, tehran, iran amp;amp; biochemistry and nutrition department of zanjan medical university, zanjan


h رستگار | h rastegar
ministry of health and medical education, food amp;amp; drug laboratory research center, tehran

سازمان اصلی تایید شده: وزارت بهداشت درمان و آموزش پزشکی (Ministry of health and medical education)

sh رضازاده | sh rezazadeh
institute of medicinal plants, acecr, tehran

سازمان اصلی تایید شده: پژوهشکده‮ ‬گیاهان‮ ‬دارویی‮ ‬جهاد‮ ‬دانشگاهی (Institute of medicinal plants)

d بابازاده | d babazadeh
department of anatomical sciences, islamic azad university, bonab branch, bonab

سازمان اصلی تایید شده: دانشگاه آزاد اسلامی علوم و تحقیقات (Islamic azad university science and research branch)

a زاهدی | a zahedi
department of veterinary pathology, islamic azad university, rasht branch, rasht

سازمان اصلی تایید شده: دانشگاه آزاد اسلامی علوم و تحقیقات (Islamic azad university science and research branch)

z قنبری | z ghanbari
medical school of islamic azad university, tabriz branch, tabriz

سازمان اصلی تایید شده: دانشگاه آزاد اسلامی علوم و تحقیقات (Islamic azad university science and research branch)

نشانی اینترنتی http://jmp.ir/browse.php?a_code=A-10-176-8&slc_lang=en&sid=fa
فایل مقاله اشکال در دسترسی به فایل - ./files/site1/rds_journals/88/article-88-329651.pdf
کد مقاله (doi)
زبان مقاله منتشر شده en
موضوعات مقاله منتشر شده دامپزشکی
نوع مقاله منتشر شده پژوهشی
برگشت به: صفحه اول پایگاه   |   نسخه مرتبط   |   نشریه مرتبط   |   فهرست نشریات