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فصلنامه علمی پژوهشی گیاهان دارویی، جلد ۱، شماره ۳۳، صفحات ۱۲۴-۱۳۰
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عنوان انگلیسی Effects of Sub-inhibitory Concentrations of Essential Oils of Mentha spicata and Cumminum cyminum on Virulence Factors of Pseudomonas aeruginosa
چکیده انگلیسی مقاله Background : Pseudomonas aeruginosa is one of important opportunistic pathogen, that cases serious infections . It produces many virulence factors, and this bacterium usually is resistance against antimicrobial agents. Objective :The aim of this study was evaluate the effects of sub-MICs of essential oils of Mentha spicata and Cumminum cyminum on alginate production, biofilm formation, swimming, twitching and adhesion in P. aeruginosa 8821M. Method : Minimal inhibitory concentrations (MIC) of essential oils of Mentha spicata and Cumminum cyminum were determined by macrodilution method. Alginate production, biofilm formation, swimming, twitching and adhesion in the present of sub-MICs (1/2, 1/4 and 1/8 MIC) of essential oils were determined in mucoid P. aeruginosa 8821M and compared with controls. Results : The MICs of essential oils against P. aeruginosa for M. spicata and C. cyminum oils were obtained 16 and 32 μg/ml respectively. The results show that all oils at 1/2 and 1/4 MICs were significantly reduced all tested virulence factors. At 1/8 MICs, M. spicata had effect just on adhesion but C. cyminum had effect on Alginate production, biofilm formation, swimming and twitching . Conclusion : This study showed that sub-MIC levels of M. spicata and C. cyminum essential oils affected alginate production, biofilm formation, swimming, twitching and adhesion in P. aeruginosa 8821M and it is probable to use of these medicinal plants for treating.
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نویسندگان مقاله s موسوی ندوشن | s mousavi nadoshan
department of biology, shahed university, tehran

سازمان اصلی تایید شده: دانشگاه شاهد (Shahed university)

p اولیا | p owlia
no. 31, abdollahzadeh st., keshavarz blvd., department of microbiology, faculty of medicine, shahed university, tehran, iran, p.o.box 14155-7435, tel 009821 88964792, fax 009821 88966310

سازمان اصلی تایید شده: دانشگاه شاهد (Shahed university)

l معین نجف آبادی | l moein najafabadi
department of biology, shahed university, tehran

سازمان اصلی تایید شده: دانشگاه شاهد (Shahed university)

i رسولی | i rasooli
department of biology, shahed university, tehran

سازمان اصلی تایید شده: دانشگاه شاهد (Shahed university)

h صادری | h saderi
department of microbiology, faculty of medicine, shahed university, tehran

سازمان اصلی تایید شده: دانشگاه شاهد (Shahed university)

mh سالاری | mh salari
department of microbiology, faculty of medicine, shahed university, tehran

سازمان اصلی تایید شده: دانشگاه شاهد (Shahed university)

نشانی اینترنتی http://jmp.ir/browse.php?a_code=A-10-414-1&slc_lang=en&sid=fa
فایل مقاله اشکال در دسترسی به فایل - ./files/site1/rds_journals/88/article-88-329657.pdf
کد مقاله (doi)
زبان مقاله منتشر شده en
موضوعات مقاله منتشر شده میکروبیولوژی
نوع مقاله منتشر شده پژوهشی
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