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مجله دانشگاه علوم پزشکی مازندران، جلد ۲۶، شماره ۱۴۵، صفحات ۲۴۸-۲۵۶

عنوان فارسی بررسی سم آفلاتوکسین M۱ در شیر گاومیش با استفاده از روش ایمنواسی
چکیده فارسی مقاله سابقه و هدف: مایکوتوکسین‌ها گروهی از ترکیبات سمی طبیعی بوده که توسط گونه‌های متعددی از قارچ‌ها تولید می‌شوند که آفلاتوکسین‌ها مهم‌ترین آن‌ها است.آفلاتوکسین‌های M1و M2 مشتقاتی از آفلاتوکسین‌های B1 وB2 هستند که در مقابل تغییرات حرارتی از قبیل پاستوریزه کردن، استریلیزاسیون و اتوکلاو کردن مقاومت نشان داده در نتیجه غلظت آن‌ها کاهش پیدا نمی‌کند لذا توسط شیر و محصولات لبنی به انسان منتقل شده و سلامت انسان و جامعه را به خطر می‌اندازد. هدف از انجام این مطالعه بررسی آفلاتوکسینM1 در شیر گاومیش‌های دو شهرستان اهواز و کارون با استفاده از روش الایزا بوده است. مواد و روش‌ها: در این مطالعه توصیفی- تحلیلی 60 نمونه شیر به‌طور اتفاقی از 2دامداری که بیش‌ترین راس را در دو منطقه داشتند و در3 ماه از فصل پاییز(مهر، آبان، آذر) جمع‌آوری شد و روش الایزا برای تعیین آفلاتوکسین موجود در نمونه‌های شیر گاومیش استفاده شد. یافته‌ها: میانگین غلظت سم آفلاتوکسین M1 درکل نمونه‌های دو منطقه نامبرده طی سه ماه متوالیاز حد مجاز استاندارد ایران، اتحادیه اروپا(کدکس)و سازمان غذا بیش‌تر(91/155 ng/l) بود. استنتاج: طبق بررسی‌های انجام شده در مطالعه حاضر رابطه تنگاتنگی بین نوع جیره غذایی و روش نگهداری خوراک دام با میزان سم در شیر وجود داشت.
کلیدواژه‌های فارسی مقاله آفلاتوکسین M1، شیر، ایمنی غذا، الایزا

عنوان انگلیسی Investigating Aflatoxin M1 Contamination in Buffalos Milk Using Immunoassay
چکیده انگلیسی مقاله Background and purpose: Mycotoxins are a group of toxic compounds produced by several species of fungi and aflatoxins are the most important toxins. M1 and M2 which are derivatives of aflatoxin B1 and B2 are resistant against thermal changes, such as pasteurization, sterilization and autoclave and their concentration will not decrease. They are transmitted to humans by milk and milk products and threaten the health of human and society. The aim of this study was to determine aflatoxin M1 in buffaloes milk in Ahvaz and Karoon, Iran using ELIZA method. Materials and methods: In a cross-sectional study, 60 milk samples were randomly collected from two farms with large number of buffalos, in autumn. ELISA method was used to evaluate of aflatoxins the samples. Results: The average level of aflatoxin M1 in two selected locations was (155.91 ng/l) which was more than standard level in Iran and the Codex Alimentarius. Conclusion: According to this research, there was a strong relationship between presence of toxin in milk with the animals’ diet and method of storing their foods.Background and purpose: Mycotoxins are a group of toxic compounds produced by several species of fungi and aflatoxins are the most important toxins. M1 and M2 which are derivatives of aflatoxin B1 and B2 are resistant against thermal changes, such as pasteurization, sterilization and autoclave and their concentration will not decrease. They are transmitted to humans by milk and milk products and threaten the health of human and society. The aim of this study was to determine aflatoxin M1 in buffaloes milk in Ahvaz and Karoon, Iran using ELIZA method. Materials and methods: In a cross-sectional study, 60 milk samples were randomly collected from two farms with large number of buffalos, in autumn. ELISA method was used to evaluate of aflatoxins the samples. Results: The average level of aflatoxin M1 in two selected locations was (155.91 ng/l) which was more than standard level in Iran and the Codex Alimentarius. Conclusion: According to this research, there was a strong relationship between presence of toxin in milk with the animals’ diet and method of storing their foods. Background and purpose: Mycotoxins are a group of toxic compounds produced by several species of fungi and aflatoxins are the most important toxins. M1 and M2 which are derivatives of aflatoxin B1 and B2 are resistant against thermal changes, such as pasteurization, sterilization and autoclave and their concentration will not decrease. They are transmitted to humans by milk and milk products and threaten the health of human and society. The aim of this study was to determine aflatoxin M1 in buffaloes milk in Ahvaz and Karoon, Iran using ELIZA method. Materials and methods: In a cross-sectional study, 60 milk samples were randomly collected from two farms with large number of buffalos, in autumn. ELISA method was used to evaluate of aflatoxins the samples. Results: The average level of aflatoxin M1 in two selected locations was (155.91 ng/l) which was more than standard level in Iran and the Codex Alimentarius. Conclusion: According to this research, there was a strong relationship between presence of toxin in milk with the animals’ diet and method of storing their foods.Background and purpose: Mycotoxins are a group of toxic compounds produced by several species of fungi and aflatoxins are the most important toxins. M1 and M2 which are derivatives of aflatoxin B1 and B2 are resistant against thermal changes, such as pasteurization, sterilization and autoclave and their concentration will not decrease. They are transmitted to humans by milk and milk products and threaten the health of human and society. The aim of this study was to determine aflatoxin M1 in buffaloes milk in Ahvaz and Karoon, Iran using ELIZA method. Materials and methods: In a cross-sectional study, 60 milk samples were randomly collected from two farms with large number of buffalos, in autumn. ELISA method was used to evaluate of aflatoxins the samples. Results: The average level of aflatoxin M1 in two selected locations was (155.91 ng/l) which was more than standard level in Iran and the Codex Alimentarius. Conclusion: According to this research, there was a strong relationship between presence of toxin in milk with the animals’ diet and method of storing their foods. Background and purpose: Mycotoxins are a group of toxic compounds produced by several species of fungi and aflatoxins are the most important toxins. M1 and M2 which are derivatives of aflatoxin B1 and B2 are resistant against thermal changes, such as pasteurization, sterilization and autoclave and their concentration will not decrease. They are transmitted to humans by milk and milk products and threaten the health of human and society. The aim of this study was to determine aflatoxin M1 in buffaloes milk in Ahvaz and Karoon, Iran using ELIZA method. Materials and methods: In a cross-sectional study, 60 milk samples were randomly collected from two farms with large number of buffalos, in autumn. ELISA method was used to evaluate of aflatoxins the samples. Results: The average level of aflatoxin M1 in two selected locations was (155.91 ng/l) which was more than standard level in Iran and the Codex Alimentarius. Conclusion: According to this research, there was a strong relationship between presence of toxin in milk with the animals’ diet and method of storing their foods.Background and purpose: Mycotoxins are a group of toxic compounds produced by several species of fungi and aflatoxins are the most important toxins. M1 and M2 which are derivatives of aflatoxin B1 and B2 are resistant against thermal changes, such as pasteurization, sterilization and autoclave and their concentration will not decrease. They are transmitted to humans by milk and milk products and threaten the health of human and society. The aim of this study was to determine aflatoxin M1 in buffaloes milk in Ahvaz and Karoon, Iran using ELIZA method. Materials and methods: In a cross-sectional study, 60 milk samples were randomly collected from two farms with large number of buffalos, in autumn. ELISA method was used to evaluate of aflatoxins the samples. Results: The average level of aflatoxin M1 in two selected locations was (155.91 ng/l) which was more than standard level in Iran and the Codex Alimentarius. Conclusion: According to this research, there was a strong relationship between presence of toxin in milk with the animals’ diet and method of storing their foods. Background and purpose: Mycotoxins are a group of toxic compounds produced by several species of fungi and aflatoxins are the most important toxins. M1 and M2 which are derivatives of aflatoxin B1 and B2 are resistant against thermal changes, such as pasteurization, sterilization and autoclave and their concentration will not decrease. They are transmitted to humans by milk and milk products and threaten the health of human and society. The aim of this study was to determine aflatoxin M1 in buffaloes milk in Ahvaz and Karoon, Iran using ELIZA method. Materials and methods: In a cross-sectional study, 60 milk samples were randomly collected from two farms with large number of buffalos, in autumn. ELISA method was used to evaluate of aflatoxins the samples. Results: The average level of aflatoxin M1 in two selected locations was (155.91 ng/l) which was more than standard level in Iran and the Codex Alimentarius. Conclusion: According to this research, there was a strong relationship between presence of toxin in milk with the animals’ diet and method of storing their foods.Background and purpose: Mycotoxins are a group of toxic compounds produced by several species of fungi and aflatoxins are the most important toxins. M1 and M2 which are derivatives of aflatoxin B1 and B2 are resistant against thermal changes, such as pasteurization, sterilization and autoclave and their concentration will not decrease. They are transmitted to humans by milk and milk products and threaten the health of human and society. The aim of this study was to determine aflatoxin M1 in buffaloes milk in Ahvaz and Karoon, Iran using ELIZA method. Materials and methods: In a cross-sectional study, 60 milk samples were randomly collected from two farms with large number of buffalos, in autumn. ELISA method was used to evaluate of aflatoxins the samples. Results: The average level of aflatoxin M1 in two selected locations was (155.91 ng/l) which was more than standard level in Iran and the Codex Alimentarius. Conclusion: According to this research, there was a strong relationship between presence of toxin in milk with the animals’ diet and method of storing their foods. Background and purpose: Mycotoxins are a group of toxic compounds produced by several species of fungi and aflatoxins are the most important toxins. M1 and M2 which are derivatives of aflatoxin B1 and B2 are resistant against thermal changes, such as pasteurization, sterilization and autoclave and their concentration will not decrease. They are transmitted to humans by milk and milk products and threaten the health of human and society. The aim of this study was to determine aflatoxin M1 in buffaloes milk in Ahvaz and Karoon, Iran using ELIZA method. Materials and methods: In a cross-sectional study, 60 milk samples were randomly collected from two farms with large number of buffalos, in autumn. ELISA method was used to evaluate of aflatoxins the samples. Results: The average level of aflatoxin M1 in two selected locations was (155.91 ng/l) which was more than standard level in Iran and the Codex Alimentarius. Conclusion: According to this research, there was a strong relationship between presence of toxin in milk with the animals’ diet and method of storing their foods. Background and purpose: Mycotoxins are a group of toxic compounds produced by several species of fungi and aflatoxins are the most important toxins. M1 and M2 which are derivatives of aflatoxin B1 and B2 are resistant against thermal changes, such as pasteurization, sterilization and autoclave and their concentration will not decrease. They are transmitted to humans by milk and milk products and threaten the health of human and society. The aim of this study was to determine aflatoxin M1 in buffaloes milk in Ahvaz and Karoon, Iran using ELIZA method. Materials and methods: In a cross-sectional study, 60 milk samples were randomly collected from two farms with large number of buffalos, in autumn. ELISA method was used to evaluate of aflatoxins the samples. Results: The average level of aflatoxin M1 in two selected locations was (155.91 ng/l) which was more than standard level in Iran and the Codex Alimentarius. Conclusion: According to this research, there was a strong relationship between presence of toxin in milk with the animals’ diet and method of storing their foods.
کلیدواژه‌های انگلیسی مقاله aflatoxin M1, milk, food safety, ELISA

نویسندگان مقاله حوریا غریبی | huria ghariby
msc student in environmental health,, school of public health, ahvaz jundishapur university of medical sciences, ahvaz, iran
اهواز دانشگاه علوم پزشکی جندی شاپور اهواز، مرکز تحقیقات فناوریهای زیست محیطی –اهواز -ایران
سازمان اصلی تایید شده: دانشگاه علوم پزشکی جندی شاپور اهواز (Ahvaz jundishapur university of medical sciences)

افشین تکدستان | afshin takdastan
associate professor, environmental technologies research center, ahvaz jundishapur university of medical sciences, ahvaz, iran
دانشگاه علوم پزشکی جندی شاپور اهواز، مرکز تحقیقات فناوری های زیست محیطی
سازمان اصلی تایید شده: دانشگاه علوم پزشکی جندی شاپور اهواز (Ahvaz jundishapur university of medical sciences)

عبدالکاظم نیسی | abdol kazem neisi
assistant professor, department of e environmental health , school of public health, ahvaz jundishapur university of medical sciences, ahvaz, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی جندی شاپور اهواز (Ahvaz jundishapur university of medical sciences)

حمیده رضازاده | hamideh rezazadeh
msc student in environmental health,, school of public health, ahvaz jundishapur university of medical sciences, ahvaz, iran
دانشجوی ارشد مهندسی بهداشت محیط، دانشکده بهداشت، دانشگاه علوم پزشکی جندی شاپور اهواز، اهواز، ایران
سازمان اصلی تایید شده: دانشگاه علوم پزشکی جندی شاپور اهواز (Ahvaz jundishapur university of medical sciences)

حسن کوهپایی | hasan kuhpaee
msc student in industrial safety engineering, faculty of health, safety and environment, shahid beheshti university of medical sciences, tehran, iran
دانشجوی ارشد ایمنی و محیط زیست، دانشکده سلامت ، دانشگاه علوم پزشکی شهید بهشتی، تهران، ایران
سازمان اصلی تایید شده: دانشگاه علوم پزشکی شهید بهشتی (Shahid beheshti university of medical sciences)


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