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Iranian Journal of Public Health، جلد ۵۳، شماره ۱۱، صفحات ۲۴۳۲-۲۴۳۹
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عنوان انگلیسی The Role of Osteocalcin in Patients with Osteoporosis: A Systematic Review
چکیده انگلیسی مقاله Background: Osteoporosis is the most common systemic skeletal disease worldwide. We aimed to review the latest studies related to osteocalcin and osteoporosis to clarify this relationship more precisely. Methods: A systematic literature search was performed to review studies on the effects of osteocalcin on osteoporosis, on studied published between January 2013 and January 2023. We systematically reviewed Web of Science, PubMed, ProQuest, Scopus, and Google Scholar. Results: The search yielded 4903 records, including 1063 from PubMed, 2307 from Scopus, 1084 from Web of Science, 408 from ProQuest, and 41 from Google Scholar, and twelve articles were included for data extraction and quality assessment. A significant increase in the serum level of osteocalcin was observed in postmenopausal women with osteoporosis (P<0.05), and there was a negative correlation between bone mineral density and the serum level of osteocalcin. Conclusion: Osteocalcin could be a promising marker for the diagnosis and screening of patients with osteoporosis.
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نویسندگان مقاله | Seyed Mohammad Mohammadi
Department of Orthopedics, School of Medicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran


| Nadia Saniee
Department of Basic Science, Asadabad School of Medical Sciences, Asadabad, Iran


| Sajedeh Mousaviasl
Department of Nursing, School of Nursing, Abadan University of Medical Sciences, Abadan, Iran


| Esmat Radmanesh
Department of Physiology, School of Medicine, Abadan University of Medical Sciences, Abadan, Iran


| Amir Hossein Doustimotlagh
Department of Clinical Biochemistry, Faculty of Medicine, Yasuj University of Medical Sciences, Yasuj, Iran
نشانی اینترنتی https://ijph.tums.ac.ir/index.php/ijph/article/view/33346
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