این سایت در حال حاضر پشتیبانی نمی شود و امکان دارد داده های نشریات بروز نباشند
Journal of Research in Medical Sciences، جلد ۱۷، شماره ۰۳، صفحات ۰-۰
عنوان فارسی
چکیده فارسی مقاله
کلیدواژه‌های فارسی مقاله
عنوان انگلیسی Effect of vitamin E on decreasing post-operative adhesion in rat uterine horn
چکیده انگلیسی مقاله Normal 0 false false false EN-US X-NONE AR-SA MicrosoftInternetExplorer4 BACKGROUND : Adhesions, as abnormal scared tissue, are common following gynecological operations and can cause chronic pelvic pain, infertility, poor outcomes of future surgeries, and intestinal obstruction. Oxygen free radicals are known as one of the main causes of adhesion formation. This study is to evaluate the effect of vitamin E on decreasing post operative adhesion in uterine horn of rats. METHODS : This experimental study was performed on 45 non-pregnant female rats randomly placed into 3 equal groups. In all groups after general anesthesia and sterile exploration, anti-mesenteric surface of the left uterine horn of the rats was traumatized using a single-polar couther. The right side was traumatized by a scalpel. Intra-peritoneal and intra-muscular vitamin E were administrated in the 1st and 2nd groups, respectively, while in the control group only normal saline solution was poured onto the horns. Following 4 weeks recovery, second laparotomy was performed to grade the adhesions, if any. The dose of vitamin E for each rat was 10 IU (50u/kg). RESULTS : Vitamin E had no effect on preventing adhesion formation in the right uterine horn traumatized by scalpel. However, vitamin E administration in the left side (both intra-peritoneal and intra-muscular) traumatized by cautery, had a significantly preventive effect against adhesion formation. In comparison with intra-peritoneal administration, intra-muscular vitamin E had a greater protective effect. CONCLUSIONS : Considering vitamin E availability, cost-efficacy and safety, injected intra-muscularly before operations can prevent adhesion formation. KEYWORDS : Adhesion, Vitamin E, Rat Uterine Horns, Peritoneum, Laparotomy
کلیدواژه‌های انگلیسی مقاله
نویسندگان مقاله شهناز آرام | shahnaz aram
associate professor, department of obstetrics and gynecology, school of medicine, isfahan university of medical sciences, isfahan, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی اصفهان (Isfahan university of medical sciences)

فاطمه مستاجران | fatemeh mostajeran
professor, department of obstetrics and gynecology, school of medicine, isfahan university of medical sciences, isfahan, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی اصفهان (Isfahan university of medical sciences)

آذر دانش شهرکی | azar danesh shahraki
associate professor, department of obstetrics and gynecology, school of medicine, isfahan university of medical sciences, isfahan, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی اصفهان (Isfahan university of medical sciences)

شهریار ادیبی | shahriar adibi
dvm, isfahan research clinical hospital, school of medicine, isfahan university of medical sciences, isfahan, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی اصفهان (Isfahan university of medical sciences)

شکوفه شاملو | shekoofeh shamloo
school of medicine, isfahan university of medical sciences, isfahan, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی اصفهان (Isfahan university of medical sciences)

نشانی اینترنتی http://jrms.mui.ac.ir/index.php/jrms/article/view/8164
فایل مقاله اشکال در دسترسی به فایل - ./files/site1/rds_journals/218/article-218-331013.pdf
کد مقاله (doi)
زبان مقاله منتشر شده en
موضوعات مقاله منتشر شده
نوع مقاله منتشر شده Original Articles
برگشت به: صفحه اول پایگاه   |   نسخه مرتبط   |   نشریه مرتبط   |   فهرست نشریات