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Journal of Research in Medical Sciences، جلد ۱۷، شماره ۰۳، صفحات ۰-۰
عنوان فارسی
چکیده فارسی مقاله
کلیدواژه‌های فارسی مقاله
عنوان انگلیسی Prophylactic treatment of chronic tension-type headache with trigger points: comparison of oral gabapentin and local injection of depomedrol
چکیده انگلیسی مقاله Normal 0 false false false EN-US X-NONE AR-SA MicrosoftInternetExplorer4 /* Style Definitions */ table.MsoNormalTable {mso-style-name:"Table Normal"; mso-tstyle-rowband-size:0; mso-tstyle-colband-size:0; mso-style-noshow:yes; mso-style-priority:99; mso-style-qformat:yes; mso-style-parent:""; mso-padding-alt:0in 5.4pt 0in 5.4pt; mso-para-margin-top:0in; mso-para-margin-right:0in; mso-para-margin-bottom:10.0pt; mso-para-margin-left:0in; line-height:115%; mso-pagination:widow-orphan; font-size:11.0pt; font-family:"Calibri","sans-serif"; mso-ascii-font-family:Calibri; mso-ascii-theme-font:minor-latin; mso-fareast-font-family:"Times New Roman"; mso-fareast-theme-font:minor-fareast; mso-hansi-font-family:Calibri; mso-hansi-theme-font:minor-latin; mso-bidi-font-family:Arial; mso-bidi-theme-font:minor-bidi;} BACKGROUND : This study was designed to compare the effectiveness of oral gabapentin and locally injected depomedrol in trigger points (TrPts) of the head of patients suffering from chronic tension type headaches (CTTH). METHODS : In this study patients with a diagnosis of CTTH who had at least one active trigger point in their scalp were recruited. Patients were randomly divided into two groups: one receiving depomedrol and the other receiving gabapentin. Depomedrol was injected 10 mg per each TrPt up to a total dose of 40 mg in each patient. Gabapentin was initiated with 200 mg/day and was gradually increased to 300-600 mg daily depending on the therapeutic response. Patients were followed for two months and during the study patients were given a headache diary to record the number, duration and intensity of their headaches, these records were compared at baseline one month and two months after the initiation of therapy. RESULTS : Headache Intensity × Duration index showed a significant decrease in both groups. It was however, significantly lower in depomedrol receiving patients at the end of the first 4 weeks (368.13 ± 195.75 Vs. 467.73 ± 203.09, p < 0.05), and the second 4 weeks (165.44 ± 62.75 Vs. 238.68 ± 81.39, p < 0.05). Similar superiority was detectable for intensity, duration and frequency of headaches (p < 0.05). CONCLUSIONS : We found trigger point injection with depomedrol to be a more potent prophylactic agent in comparison to daily oral gabapentin. KEYWORDS : Headache, Tension, Gabapentin, Depomedrol, Prophylaxis
کلیدواژه‌های انگلیسی مقاله Headache, Tension, Gabapentin, Depomedrol, Prophylaxis
نویسندگان مقاله bahadr اسدی | bahadr asadi
aja university of medical sciences, tehran, iran


فریبرز خوروش | fariborz khorvash
department of neurolog, school of medicine and isfahan neurosciences research center, school of medicine, isfahan university of medical sciences, isfahan, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی اصفهان (Isfahan university of medical sciences)

فرزاد محرابی | farzad mehrabi
aja university of medical sciences, tehran, iran


ابوالفضل نجاران | abolfazl najjaran
aja university of medical sciences, tehran, iran


مجید قاسمی | majid ghasemi
department of neurolog, school of medicine and isfahan neurosciences research center, school of medicine, isfahan university of medical sciences, isfahan, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی اصفهان (Isfahan university of medical sciences)

سید علی موسوی | seyed ali mousavi
department of neurolog, school of medicine and isfahan neurosciences research center, school of medicine, isfahan university of medical sciences, isfahan, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی اصفهان (Isfahan university of medical sciences)

نشانی اینترنتی http://jrms.mui.ac.ir/index.php/jrms/article/view/7254
فایل مقاله اشکال در دسترسی به فایل - ./files/site1/rds_journals/218/article-218-331015.pdf
کد مقاله (doi)
زبان مقاله منتشر شده en
موضوعات مقاله منتشر شده
نوع مقاله منتشر شده Original Articles
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