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International Journal of Radiation Research، جلد ۲۲، شماره ۴، صفحات ۸۳۷-۸۴۳
عنوان فارسی
چکیده فارسی مقاله
کلیدواژه‌های فارسی مقاله
عنوان انگلیسی A comparative planning study on the treatment of gastric cancer patients with tomotherapy, coplanar and non-coplanar three-dimensional conformal radiotherapy (3D-CRT)
چکیده انگلیسی مقاله
Background: The main purpose of this study is to investigate different methods of radiotherapy (RT) using coplanar three-dimensional conformal RT (3D-CRT (cp)), non-coplanar 3D-CRT RT (3D-CRT (ncp)) and helical tomotherapy (HT) techniques to find the optimal method to treat gastric cancer patients. Materials and Methods: Twenty patients with gastric cancer were retrospectively enrolled. Three different treatment plans including HT, 3D-CRT (cp) and 3D-CRT (ncp) were generated and optimized for each patient. All plans were then evaluated with respect to dosimetric parameters exported from dose-volume histogram curves of target and organ-at-risk (OAR). SPSS software was used for statistical analysis. Results: The conformity index in the target was similar for all plans (p > 0.05), but HT showed significantly better homogeneity compared to the two 3D-CRT methods (p-value < 0.05). Compared to the 3D-CRT (cp) and 3D-CRT (ncp) plans, the HT plans significantly reduced the mean dose, V13 and V20 values of the kidneys (p-Value < 0.05); V5 values of both kidneys were lower in the 3D-CRT (ncp) plan compared to 3D-CRT (cp) and HT. The difference was statistically significant. Moreover, the results proved that the 3D-CRT (ncp) could better preserve kidneys rather than 3D-CRT (cp). Dmean of the liver for HT plans (20.03) was significantly higher than those for both coplanar and non-coplanar 3D-CRT plans (17.86 and 17.7, respectively). Conclusion: Generally, HT plans appear to be the best, but in the case of selecting an optimum method, it is necessary to pay attention to the location of tumors compared to OARs.
کلیدواژه‌های انگلیسی مقاله Gastric cancer, helical tomotherapy, three‑dimensional conformal radiotherapy.
نویسندگان مقاله | A. Kazemzadeh
Department of Medical Physics, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran


| L. Mahani
Department of Radio-Oncology, Seyed-Al-Shohada Hospital, Isfahan University of Medical Sciences, Isfahan, Iran


| M. Kianinia
Department of Radio-Oncology, Seyed-Al-Shohada Hospital, Isfahan University of Medical Sciences, Isfahan, Iran


| A. Shanei
Department of Medical Physics, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran
نشانی اینترنتی http://ijrr.com/browse.php?a_code=A-10-1-1247&slc_lang=en&sid=1
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کد مقاله (doi)
زبان مقاله منتشر شده en
موضوعات مقاله منتشر شده Radiation Biology
نوع مقاله منتشر شده تحقیق بدیع
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