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مجله علوم اعصاب شفای خاتم، جلد ۳، شماره ۳، صفحات ۲۹-۲۹
عنوان فارسی P۱۱: The Effect of Flavonoids in Memory
چکیده فارسی مقاله لطفاً به چکیده انگلیسی مراجعه شود.
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عنوان انگلیسی P11: The Effect of Flavonoids in Memory
چکیده انگلیسی مقاله Flavonoids may exert particularly powerful actions on mammalian cognition and may reverse age-related declines in memory and learning. Flavonoids can be modulated neuronal function and there by influencing memory, learning and cognitive function. Dietary supplementation with flavonoid-rich foods, such as blueberry, green tea and Ginkgo biloba lead to significant reversals of age-related deficits on spatial memory and learning. Recently, significant evidence has appeared to show that phytochemical-rich foods, and in particular those rich in flavonoids, may reverse age related deficits in cognitive function in both animals and human subjects. To impact flavonoids on brain function, must cross the blood–brain barrier. With regard to specific brain localization, several studies report anthocyanin in different regions of the brain of both rodents and pigs after supplementation with blueberry. Animal investigations have evidently denoted that flavonoid-rich foods are beneficial in retarding and/or counteracting functional age-related cognitive deficits. There is robust evidence that flavonoid-rich foods can impact on memory and learning and that this seems likely to involve, to some degree, regulation of signaling cascades, leading to changes in morphological aspects of neuronal cells that ultimately impact on synaptic plasticity and more sustained long term potentiation in the hippocampus. Studies suggest that flavonoid-rich foods are capable of inducing improvements in memory and cognition in animals and humans. There is evidence to suggest that blueberry flavonoids can cross the blood-brain barrier and reach the central nervous system, where they have the potential to directly regulate gene and protein expression in neurons. Flavonoids are likely causal agents in mediating the cognitive effects.
کلیدواژه‌های انگلیسی مقاله Flavonoids, Memory, Cognitive Effects
نویسندگان مقاله آرزو اسحق آبادی | arezou eshaghabadi
shefa neuroscience research center, khatam alanbia hospital, tehran, iran

سازمان اصلی تایید شده: مرکز تحقیقات علوم اعصاب شفا (Shefa neuroscience research center)

سجاد سحاب نگاه | sajad sahab negah
shefa neuroscience research center, khatam alanbia hospital, tehran, iran

سازمان اصلی تایید شده: مرکز تحقیقات علوم اعصاب شفا (Shefa neuroscience research center)

نشانی اینترنتی http://shefayekhatam.ir/browse.php?a_code=A-10-24-597&slc_lang=en&sid=fa
فایل مقاله اشکال در دسترسی به فایل - ./files/site1/rds_journals/337/article-337-332178.pdf
کد مقاله (doi)
زبان مقاله منتشر شده fa
موضوعات مقاله منتشر شده تحقیقات پایه در علوم اعصاب
نوع مقاله منتشر شده مروری
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