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Nanomedicine Journal، جلد ۱۲، شماره ۱، صفحات ۱-۱۴
عنوان فارسی
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عنوان انگلیسی The role of platelet derived exosomes in regenerative medicine
چکیده انگلیسی مقاله Exosomes are a group of extracellular vesicles that are produced by various cells and are abundantly found in body fluids such as plasma. Due to their special structure, these small particles are able to carry and contain various compounds and establish cellular communication. Also, much attention has been paid to the ability of exosomes as new treatment option in various fields of regenerative medicine. One of the most abundant exosomes in plasma is platelet derived exosomes, which are rich in compounds found in platelet granules, such as growth factors. Since the use of platelets and platelet-rich plasma has been very effective in regenerative medicine, in recent years the use of platelet exosomes in regenerative medicine has received much attention and investigation. This review briefly examines the role of platelet exosomes in various fields of regenerative medicine, such as hair repair, wound healing, orthopedic injuries, angiogenesis, and drug delivery. The results of this study show that these microparticles have low immunogenicity, low thrombogenicity, and they are very useful and efficient in regenerative medicine. 
کلیدواژه‌های انگلیسی مقاله Exosomes, Growth factors, Platelets, Regenerative medicine 
نویسندگان مقاله | Seyyede Fatemeh Shams
Department of hematology and blood banking. Faculty of medicine. Mashhad University of medical sciences, Mashhad, Iran|Cancer Molecular Pathology Research Center, Mashhad University of Medical Sciences,Mashhad, Iran


| Mohammadreza Javan
Department of Anatomy, Physiology and Pharmacology, University of Saskatchewan, Saskatoon, Canada


| Faeze Shahriyari
Blood Transfusion Research Center, High Institute for Research and Education in Transfusion Medicine, Iranian Blood Transfusion Organization (IBTO), Tehran, Iran
نشانی اینترنتی https://nmj.mums.ac.ir/article_24853.html
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زبان مقاله منتشر شده en
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نوع مقاله منتشر شده Review Paper
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