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Middle East Journal of Digestive Diseases، جلد ۱۶، شماره ۴، صفحات ۲۴۲-۲۴۹
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عنوان انگلیسی Evaluation of Hematological Parameters as Markers for Subclinical Inflammation in Adults with Familial Mediterranean Fever
چکیده انگلیسی مقاله Background: Repeated polyserositis, another name for familial Mediterranean fever (FMF), is an autoimmune disorder with an autosomal recessive nature primarily characterized by short-lived repeated periods of peritonitis, pleuritis, and arthritis, generally accompanied by fever. Methods : Our participants were divided into two groups. Group I (patients): 100 individuals who were diagnosed  as patients with FMF and were monitored. Group II (control): matched- healthy individuals (100 controls). They were compared and followed up as regards demographic, clinical, and laboratory data: routine investigations, neutrophil/lymphocyte ratio (NLR), platelet lymphocyte ratio (PLR), and mean packed volume (MPV), red cell distribution width (RDW), C-reactive protein (CRP), and erytherocyte sedmintation rate(ESR). Results: Group I: MPV mean was 12.03±2.89, whereas group II MPV mean was 7.74±0.57. MPV was significantly statistically greater in group I than in group II. RDW mean in group I was 17.07±1.39 and in group II was 12.92±0.63. RDW was also significantly statistically greater in group I compared with group II. Group I's NLR mean was 3.05±0.71, whereas group II's NLR mean was 1.75±0.2. PLR mean in group I was 164.8±122.8 and in group II was 111.26±29.16. Conclusion: A statistically significant association was shown between the diagnosis of adult FMF and NLR, PLR, MPV, and RDW.
کلیدواژه‌های انگلیسی مقاله Familial Mediterranean fever (FMF),Red blood cell distribution width (RDW),Mean platelet volume (MPV),Neutrophil to leukocyte ratio (NLR),Platelet to lymphocyte ratio (PLR)
نویسندگان مقاله | Mohamed Gamal Abd Rabou
Alexandria University, Faculty of Medicine, Department of Internal Medicine, Alexandria, Egypt


| Ali Mahmoud Ramadan
Alexandria University, Faculty of Medicine, Department of Internal Medicine, Alexandria, Egypt


| Ahmed Mohamed Mohsen
Alexandria University, High Institute of Public Health, Department of Epidemiology, Alexandria, Egypt


| Marwa Shawky


نشانی اینترنتی http://mejdd.org/index.php/mejdd/article/view/3186
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کد مقاله (doi) 10.15171/middle east j di.v16i4.3186
زبان مقاله منتشر شده en
موضوعات مقاله منتشر شده
نوع مقاله منتشر شده Original Article
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