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Iranian Journal of Microbiology، جلد ۱۶، شماره ۶، صفحات ۷۳۷-۷۴۴
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عنوان انگلیسی Lessons from an 11-year retrospective cohort study of Escherichi coli causing UTI in Imam Hospital Ardabil, Iran
چکیده انگلیسی مقاله Background and Objectives: The global problem of urinary tract infections (UTIs) caused by antibiotic-resistant bacteria is due to limited treatment options. This study aimed to examine the prevalence, etiology, and management implications of Escherichi coli causing UTI at Imam Hospital Ardabil, Iran. Materials and Methods: 2340 samples of retrospective data on E. coli causing UTIs were collected at Imam Hospital in Ardabil, Iran, spanning from 2012 to 2022. The samples were cultured and isolated, and their antibiotic susceptibility was determined using standard laboratory methods and data were then organized and systematically categorized using Python. Results: It was found that the lowest level of resistance was related to nitrofurantoin, followed by imipenem. In 2018, the number of E. coli patients resistant to trimethoprim was the highest. Cephalexin and ciprofloxacin trends indicate the reduction of the line during this retrospective period. There was a significant correlation between wards and some antibiotics like Cefepime, Cefotaxime, Ceftazidime, and Trimethoprim (P-Value <0.05). Conclusion: Significant correlations were identified between specific hospital wards and resistance to antibiotics. These findings underscore the need for continuous surveillance and tailored antibiotic stewardship programs to combat the rising trend of antibiotic resistance.
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نویسندگان مقاله | Pegah Shakib
Razi Herbal Medicines Research Center, Department of Microbiology, School of Medicine, Lorestan University of Medical Sciences, Khorramabad, Iran


| Mohsen Arzanlou
Department of Microbiology, School of Medicine, Ardabil University of Medical Sciences, Ardabil, Iran


| Pouria Sobhi
Student Research Committee, Ardabil University of Medical Sciences, Ardabil, Iran


| Mehdi Mojebi
Student Research Committee, Ardabil University of Medical Sciences, Ardabil, Iran


| Mohammad Bahrami
Student Research Committee, Ardabil University of Medical Sciences, Ardabil, Iran


| Faraz Mahdizadeh
Student Research Committee, Ardabil University of Medical Sciences, Ardabil, Iran


| Leyla Asadi
Imam Hospital Laboratory, School of Medicine, Ardabil University of Medical Sciences, Ardabil, Iran


| Masoud Amanzadeh
Department of Health Information Management, School of Medicine, Ardabil University of Medical Sciences, Ardabil, Iran


| Alireza Mohammadnia
Department of Health Information Management, School of Medicine, Ardabil University of Medical Sciences, Ardabil, Iran


| Farzad Khademi
Department of Microbiology, School of Medicine, Ardabil University of Medical Sciences, Ardabil, Iran


| Rashid Ramazanzadeh
Department of Microbiology, School of Medicine, Ardabil University of Medical Sciences, Ardabil, Iran
نشانی اینترنتی https://ijm.tums.ac.ir/index.php/ijm/article/view/4964
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