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Iranian Journal of Nursing and Midwifery Research، جلد ۳۰، شماره ۱، صفحات ۴۱-۴۶
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عنوان انگلیسی Effect of Vaginal Cream with the Combination of Honey, Olive, and Propolis on the Symptoms of Uterine Cervicitis Symptoms in Women: A Double Blind Randomized Controlled Clinical Trial Study
چکیده انگلیسی مقاله Background: Uterine cervicitis in women requires careful selection of a suitable and straightforward treatment. This study aimed to examine the effect of Nika vaginal cream on the symptoms of uterine cervicitis in women. Materials and Methods: This double-blind, randomized, controlled clinical study was conducted on 66 women who where reffered to Hamadan health centers in 2021(33 people in each group). The participants in the intervention group were instructed to use Nika vaginal cream every night for 14 nights, along with a single dose of one gram of azithromycin, 400 mg of cefixime, and 500 mg of metronidazole twice a day for both the patient and her husband. The control group received a placebo cream and the same drugs as the intervention group. After the 14-day treatment period, clinical signs were assessed through examinations, and participants completed questionnaires again. Results: The study found that participants in the Nika user group experienced a 69.70% improvement in symptoms related to uterine cervicitis. This improvement was significantly higher than the control group, which only showed a 45.50% improvement. Although the Risk Ratio (RR) between the two groups was 53% higher in the intervention group, this difference was not statistically significant ( p =0.06). However, the Risk Difference (RD) of 0.24 between the groups was found to be statistically significant ( p =0.04). Additionally, participants in the intervention group reported a 76.00% reduction in dyspareunia ( p =0.03) and an 84.00% reduction in urinary frequency ( p =0.05). Conclusions: According to the result of RD, Nika vaginal cream had a significant effect on the improvement of cervicitis symptoms.
کلیدواژه‌های انگلیسی مقاله Honey, olea, prodromal symptoms, propolis, uterine cervicitis
نویسندگان مقاله | Hamideh Parsapour
Department of Midwifery and Reproductive Health, Mother and Child Care Research Center, School of Nursing and Midwifery, Hamadan University of Medical Sciences, Hamadan, Iran


| Arezoo Shayan
Msc in Consultation in Midwifery, Department of Midwifery and Reproductive Health, School of Nursing and Midwifery, Hamadan University of Medical Sciences, Hamadan, Iran


| Mehrnoosh Hosseinpoor
Department of Midwifery and Reproductive Health, Mother and Child Care Research Center, School of Nursing and Midwifery, Hamadan University of Medical Sciences, Hamadan, Iran


| Seyedeh Zahra Masoumi
Department of Midwifery and Reproductive Health, Mother and Child Care Research Center, School of Nursing and Midwifery, Hamadan University of Medical Sciences, Hamadan, Iran


| Farideh Kazemi
Department of Pharmacognosy, School of Pharmacy, Medicinal Plants and Natural Product Research Center, Hamadan University of Medical Sciences, Hamadan, Iran


| Shirin Moradkhani
Medical Student, Medicine School, Shahid Beheshti University of Medical Sciences, Tehran, Iran,


| Oliaei
Medical Student, Medicine School, Hamadan University of Medical Sciences, Hamadan, Iran,


| Zeinab Assareh
Nika Research and Traditional MedicineProduction Company, Department of Pharmacology, Hamadan, Iran


| Mohammad Kazem Rashidi


نشانی اینترنتی http://ijnmr.mui.ac.ir/index.php/ijnmr/article/view/2193
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زبان مقاله منتشر شده en
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نوع مقاله منتشر شده Original Articles
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