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Iranian Journal of Pathology، جلد ۱۹، شماره ۴، صفحات ۴۵۳-۴۵۹

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عنوان انگلیسی A Bilateral Wolffian Adnexal Tumor with Malignant Behavior: A Rare Case Report with Literature Review
چکیده انگلیسی مقاله Wolffian adnexal tumors (FATWOs) originate from the mesonephric duct remnants. FATWOs are extremely rare, and 100 incidental FATWOs have been reported in English literature. Most FATWOs have a low potential for malignancy, but aggressive behavior, including recurrence and metastasis, has been described in a few cases; There is no standard protocol for optimal treatment of FATWOs. The case described here is a 35-year-old female who presented with a right-side ovarian mass via abdominal ultrasound. She had a history of left salpingo-oophorectomy due to an abdominal mass, which both histopathologic and immunohistochemical study’s findings were consistent with  Wolffian tumor. Later, she underwent total abdominal hysterectomy with tumor debulking because of the probable malignant behavior of the tumor. FATWO has a heterogeneous histologic pattern,which may make its diagnosis challenging. No specific immunohistochemical markers have yet been recognized for FATWO and pathogenesis or molecular alterations are not definitive.  Therefore, there is no comprehensive recommendation for optimal clinical management of FATWO or its recurrence.
کلیدواژه‌های انگلیسی مقاله Bilateral Wolffian,adnexal tumor,Malignant Behavior,Case Report

نویسندگان مقاله Shabnam Mashhadi |
Department of Pathology, Cancer Institute, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran, Iran

Fereshteh Ameli |
Department of Pathology, Cancer Institute, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran, Iran

Shahrzad Sheikhhasani |
Gynecology Oncology Department, Vali-e-Asr Hospital, Tehran University of Medical Sciences, Tehran, Iran

Sara Parviz |
Department of Radiology, School of Medicine, Imam Khomeini Hospital, Tehran University of Medical Sciences, Tehran, Iran

Fatemeh Nili |
Department of Pathology, Cancer Institute, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran, Iran

Behnaz Jahanbin |
Department of Pathology, Cancer Institute, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran, Iran

Arezoo Esmailzadeh |
Department of Obstetrics and Gynecology, Trauma Research Center, Baqiyatallah University of Medical Sciences, Tehran, Iran


نشانی اینترنتی https://ijp.iranpath.org/article_720321_94572e3e655f03efddf2572e643c6b80.pdf
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