این سایت در حال حاضر پشتیبانی نمی شود و امکان دارد داده های نشریات بروز نباشند
Iranian Journal of Microbiology، جلد ۱۷، شماره ۱، صفحات ۹۹-۱۰۵
عنوان فارسی
چکیده فارسی مقاله
کلیدواژه‌های فارسی مقاله
عنوان انگلیسی mecA and PVL genes in methicillin-resistant Staphylococcus aureus from clinical specimens: a cross-sectional hospital based study from Nepal
چکیده انگلیسی مقاله Background and Objectives: Staphylococcus aureus has increasingly been associated with community and healthcare-associated infections worldwide and contributes to treatment failures due to the emergence of multidrug-resistant (MDR) and methicillin-resistant Staphylococcus aureus (MRSA) strains. We aimed to determine the prevalence and antibiotic susceptibility pattern of MRSA isolated from patients attending a burn center and to detect mecA and PVL genes among MRSA isolates. Materials and Methods: A cross-sectional hospital based study was conducted on 1950 clinical samples collected from hospital inpatients and outpatients of Kirtipur Hospital, which is a burn specialist hospital in Kathmandu, Nepal. Each sample underwent conventional cultural methods for bacterial isolates identification. Results: Out of 1950 samples, 452 (23.2%) samples showed bacterial growth, of which 109 isolates (24.1%) were identified as Gram positive and 343 (75.9%) as Gram negative bacteria. Among the Gram positive bacteria, 53 (48.62%) were Staphylococcus aureus. Of the total S. aureus isolates, 40 (75.5%) were MRSA and 48 (90.6%) were MDR. Of the 40 MRSA isolates, 29 (72.5%) carried the mecA gene and 3 (7.5%) harbored PVL gene. Conclusion: The high prevalence of MRSA in a burn unit underscores the need for more rigorous infection control practices that follow standard protocols to reduce MRSA transmission in both individuals and the hospital environment.
کلیدواژه‌های انگلیسی مقاله
نویسندگان مقاله | Sirjana Adhikari
Central Department of Microbiology, Tribhuvan University, Kirtipur, Kathmandu, Nepal


| Supriya Sharma
Central Department of Microbiology, Tribhuvan University, Kirtipur, Kathmandu, Nepal


| Sanjib Adhikari
Central Department of Microbiology, Tribhuvan University, Kirtipur, Kathmandu, Nepal


| Sanjit Shrestha
Department of Pathology, Kirtipur Hospital, Kirtipur, Kathmandu, Nepal


| Dwij Bhatta
Central Department of Microbiology, Tribhuvan University, Kirtipur, Kathmandu, Nepal
نشانی اینترنتی https://ijm.tums.ac.ir/index.php/ijm/article/view/5035
فایل مقاله فایلی برای مقاله ذخیره نشده است
کد مقاله (doi)
زبان مقاله منتشر شده
موضوعات مقاله منتشر شده
نوع مقاله منتشر شده
برگشت به: صفحه اول پایگاه   |   نسخه مرتبط   |   نشریه مرتبط   |   فهرست نشریات