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Iranian Journal of Pathology، جلد ۲۰، شماره ۱، صفحات ۱۳۲-۱۳۶
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عنوان انگلیسی Effect of Laparoscopic Sleeve Gastrectomy on Hypothyroidism in Patients with Morbid Obesity: A one-year follow-up Prospective Cohort Study
چکیده انگلیسی مقاله Background & Objective: Obesity is a growing public health problem worldwide. Bariatric surgery is considered the safest and most effective therapeutic option, although it is associated with various metabolic and neurohormonal consequences. This study aims to evaluate the effect of sleeve gastrectomy (SG) on hypothyroidism within one year following surgery.
Methods: In this single-center prospective cross-sectional study, patients with morbid obesity who were candidates for SG were included. Body mass index (BMI), levothyroxine dosage, and thyroid function tests were compared at baseline and 12 months after surgery.
Results & Conclusion: Patients’ BMI, levothyroxine dosage, TSH, and T4 levels decreased significantly after surgery (P<0.0001). The effect of SG on T3 levels was not statistically significant. The results of this study demonstrate that SG can significantly improve thyroid function tests in patients with morbid obesity and reduce their need for levothyroxine within one year following surgery. 
کلیدواژه‌های انگلیسی مقاله Bariatric surgery,Hypothyroidism,Morbid obesity,Sleeve gastrectomy
نویسندگان مقاله Nasser Malekpour Alamdari |
Critical Care Quality Improvement Research Center, Shahid Modarres Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran

Iman Ansari |
General Surgery Department, Shahid Modarres Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran

Mohammad Ali Azizi Nadian |
General Surgery Department, Shahid Modarres Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran

Mahdiyeh Sadat Seyyedi |
Critical Care Quality Improvement Research Center, Shahid Modarres Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran

Maryam Abbasi |
Critical Care Quality Improvement Research Center, Shahid Modarres Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran

نشانی اینترنتی https://ijp.iranpath.org/article_721063_4e9dca471b222a5f6ac60a6261d81dae.pdf
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