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Middle East Journal of Digestive Diseases، جلد ۱۰، شماره ۱، صفحات ۱۲-۱۸
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عنوان انگلیسی Efficacy, Safety, and Tolerance of Split Dose Oral Sulfate Solution Versus Split-Dose Polyethylene Glycol Versus Single Dose Polyethylene Glycol for Colonoscopy Preparation: A Prospective Randomized Study
چکیده انگلیسی مقاله Background : To compare the efficacy, safety, and tolerance of three bowel preparation regimens for colonoscopy: split dose of oral sulfate solution (OSS), split dose of polyethylene glycol (PEG), and same-day single dose PEG. Methods: This study was a randomized, single-blind control design with three study groups. Group A received a split dose of OSS, group B received a split dose of PEG, and Group C received a single dose of PEG for bowel preparation. The quality of preparation was assessed using the Boston Bowel Preparation Scale (BBPS), and the adverse effects and tolerance were noted. The data were compared statistically for any significant difference between the regimens.  Results:  Mean total BBPS scores were 8.08, 7.52, and 7.92 for groups A, B, and C, respectively (P=0.076). Segmental BBPS scores were statistically similar for the right and transverse colon but differed for the left colon (A: B: C = 2.79: 2.54: 2.75; P<0.01). Gastrointestinal side effects and electrolyte disturbances were similar across the three groups. Split-dose preparations were associated with more significant sleep disturbances than single-dose PEG (p <0.001). Patients who received OSS reported more taste intolerance (P<0.01), while those who received single PEG reported more volume intolerance (P<0.001).   Conclusion: Split-dose OSS, split-dose PEG, and single-dose PEG regimens provide adequate and comparable bowel preparation for colonoscopy with good patient tolerance and no significant adverse effects. Overnight PEG and OSS preparations were associated with more substantial sleep disturbances. OSS is associated with more taste intolerance, while single PEG is associated with more volume intolerance.       
کلیدواژه‌های انگلیسی مقاله Colonoscopy, Split dose bowel preparation, PEG, Oral sulfate solution, OSS, BBPS
نویسندگان مقاله | George Sarin Zacharia
Malabar Medical College Hospital and Research Center, Calicut, Kerala, India


| Varghese Thomas


نشانی اینترنتی http://mejdd.org/index.php/mejdd/article/view/3144
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