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Iranian Journal of Medical Sciences، جلد ۵۰، شماره ۴، صفحات ۲۲۰-۲۲۸
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عنوان انگلیسی Epidemiology of Hepatitis D Virus and Associated Factors in Patients Referred to Level Three Hepatitis Clinic, Fars Province, Southern Iran
چکیده انگلیسی مقاله Background: Hepatitis D is caused by the hepatitis D virus (HDV) and affects those who have already been infected with the hepatitis B virus (HBV). The epidemiology of hepatitis D in Fars Province, Iran, is poorly understood. This study aimed to investigate the epidemiology of HDV and its associated factors in patients attending Shahid Motahari Clinic, affiliated with Shiraz University of Medical Sciences (Shiraz, Iran).
Methods: This prospective cohort study was conducted in Shiraz, Iran, from 2001 to 2023. This study screened individuals with low HBV viral load and elevated liver enzymes for HDV. Pearson Chi square, Fisher’s exact, and Mann-Whitney U tests were used to examine the univariate associations between hepatitis D and various risk factors. Risk factors with P<0.2 were analyzed using multiple logistic regression to estimate odds ratios and 95% confidence intervals. P<0.05 was considered statistically significant.
Results: The variables were compared between the HDV+ (29) and HDV- (108). The variables of age (P=0.002) and using hookah (P=0.040) were statistically significant. The other variables examined in this study were not statistically significant. Increasing age (OR=1.06, 95% CI=[1.019, 1.102], P=0.003) was identified as a risk factor, while dental visits (OR=0.290 95% CI=[0.101, 0.836], P=0.022) were assessed as a protective factor.
Conclusion: Age was a significant risk factor for HDV infection, while a history of dental procedures appeared to be a protective factor. To better understand the epidemiology of HDV, further comprehensive research is necessary, focusing on diverse demographic groups in different regions.
کلیدواژه‌های انگلیسی مقاله Hepatitis D,Risk factors,Epidemiology,Iran
نویسندگان مقاله Ali Reza Safarpour |
Gastroenterohepatology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran

Alireza Shahedi |
Student Research Committee, School of Nursing and Midwifery, Tehran University of Medical Sciences, Tehran, Iran

Mohammad Reza Fattahi |
Gastroenterohepatology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran

Erfan Sadeghi |
Department of Biostatistics, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran

Majid Akbarzadeh |
Department of Internal Medicine, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran

Lida Ahmadi |
Gastroenterohepatology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran

Nika Nikmanesh |
Gastroenterohepatology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran

Ebrahim Fallahzadeh Abarghooee |
Department of Internal Medicine, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran

Seyedeh Azra Shamsdin |
Gastroenterohepatology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran

Hassan Akrami |
Gastroenterohepatology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran

Yousef Nikmanesh |
Gastroenterohepatology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran

نشانی اینترنتی https://ijms.sums.ac.ir/article_50648_2d242b5d083cdc765bf008b7b9beb4ea.pdf
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