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Avicenna Journal of Phytomedicine، جلد ۱۵، شماره ۳، صفحات ۱۱۴۷-۱۱۶۶
عنوان فارسی
چکیده فارسی مقاله
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عنوان انگلیسی Effects of sumac aqueous extract along with eating and drinking modification on functional dyspepsia symptoms in comparison with omeprazole: An open-label, randomized, controlled clinical trial
چکیده انگلیسی مقاله Objective: Functional dyspepsia (FD), a common gastrointestinal problem. The aim of the study was to evaluate the influence of Rhus coriaria L. (sumac) on FD.Materials and Methods: This randomized controlled clinical trial study included 104 patients aged 18 to 60 years diagnosed with FD according to the ROME IV criteria. Four groups were formed: A) sumac extract + dietary changes, B) dietary changes, C) sumac extract and D) omeprazole. During the present eight-week study, patients' FD symptoms were assessed using the Gastrointestinal Symptom Rating Scale (GSRS) in four sessions. The Nepean Dyspepsia Index (NDI-10) was used to measure the impact of the interventions on patients' quality of life.Results: The study employed generalized estimating equation (GEE) analysis and found that symptom severity decreased across all groups during the intervention period. At the fourth week, no notable difference was noted between the omeprazole group and others. After the intervention, the severity of symptoms increased, especially in the omeprazole group, resulting in a significant difference compared to other groups.Conclusion: It seems that as a complementary treatment in FD, sumac might be effective with a more lasting effect with a significantly less recurrence of symptoms.
کلیدواژه‌های انگلیسی مقاله Functional Dyspepsia, Persian Medicine, Sumac, Rhus coriaria L, Quality of life
نویسندگان مقاله | Mahdi Saravani
Golestan Research Center of Gastroenterology and Hepatology, Department of Persian Medicine, School of Persian Medicine, Golestan University of Medical Sciences, Gorgan, Iran.


| Zahra memariani
Traditional Medicine and History of Medical Sciences Research Center, Health Research Institute, Department of History of Medical Sciences, School of Persian Medicine, Babol University of Medical Sciences, Babol,IR Iran.


| Nasser Behnampour
Biostatistics Department,Faculty of Health,Golestan University of Medical Sciences,Gorgan, Iran


| Mohammadreza Seyyedmajidi
Golestan Research Center of Gastroenterology and Hepatology, Department of Persian Medicine, School of Persian Medicine, Golestan University of Medical Sciences, Gorgan, Iran.


| fatemeh kolangi
Counseling and Reproductive Health Research Centre, Department of Persian Medicine, School of medicine, Golestan University of Medical Sciences, Gorgan, Iran.
نشانی اینترنتی https://ajp.mums.ac.ir/article_25239.html
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زبان مقاله منتشر شده en
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نوع مقاله منتشر شده Original Research Article
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