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Iranian Journal of Public Health، جلد ۴۴، شماره ۲، صفحات ۱۷۶-۸۴
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عنوان انگلیسی Use of noninsulin anti diabetics for prevention and treatment of cancer- narrative review article.
چکیده انگلیسی مقاله Epidemiological evidence shows that cancer and diabetes are major causes of death in the world. Type2 diabetes increases the risk of cancer-specific mortality. This review relates diabetic therapies, diabetes and cancer.All published papers in this field were searched, looking into such databases as Science Direct, ISI Web of Knowledge, PubMed and Scopus.In cancer patients, metformin improves patient outcome and reduces cancer risk. Sulfonylureas may increase risk of cancer, but decreased risk of cancer is associated with thiazolidinediones in type 2 diabetic subjects. Metformin lowers circulating insulin and it may be important for treatment of hyperinsulinemia-associated cancers, such as colon and breast cancer.However, laboratory investigations and large-scale population based studies are required for further investigation of association of cancer-preventive, anti-cancer and cancer-mortality of noninsulin antidiabetics.
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نویسندگان مقاله صدف رعنا | sadaf raana
dept. of pharmacology and toxicology, university of veterinary and animal sciences, lahore, pakistan.


عقیل javeed | aqeel javeed
dept. of pharmacology and toxicology, university of veterinary and animal sciences, lahore, pakistan.
نشانی اینترنتی http://ijph.tums.ac.ir/index.php/ijph/article/view/3700
فایل مقاله اشکال در دسترسی به فایل - ./files/site1/rds_journals/86/article-86-350160.pdf
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