این سایت در حال حاضر پشتیبانی نمی شود و امکان دارد داده های نشریات بروز نباشند
Iranian Journal of Pathology، جلد ۲۰، شماره ۲، صفحات ۲۲۲-۲۲۶
عنوان فارسی
چکیده فارسی مقاله
کلیدواژه‌های فارسی مقاله
عنوان انگلیسی Sclerosing Angiomatoid Nodular Transformation of Spleen (SANTS); Case Report of a 12-Year-Old Patient
چکیده انگلیسی مقاله Background: Sclerosing angiomatoid nodular transformation of the spleen (SANT) is a rare, benign vascular lesion predominantly described in adults. Pediatric cases are exceptionally uncommon and present a diagnostic challenge due to nonspecific clinical presentations and imaging findings.
Case Presentation: We report the case of a 12-year-old boy presenting with recurrent abdominal pain localized around the umbilicus, accompanied by intermittent nausea over a three-month period. Physical examination revealed mild tenderness without guarding. Laboratory findings were unremarkable. Abdominal ultrasound demonstrated a hypoechoic splenic lesion, further evaluated by multidetector computed tomography (MDCT), which revealed a heterogeneous hypodense mass in the spleen. The patient underwent partial laparoscopic splenectomy. Histopathological examination showed a nodular architecture with fibrous bands, capillary-like vascular channels lined by endothelial cells, and a lymphoplasmacytic infiltrate. Immunohistochemical staining was positive for CD31, CD34, and CD8, supporting the diagnosis of SANT.
Conclusion: Although benign, SANT can mimic more aggressive splenic pathologies. This case underscores the importance of considering SANT in the differential diagnosis of splenic masses in pediatric patients and highlights the role of histopathology and immunohistochemistry in achieving a definitive diagnosis.
کلیدواژه‌های انگلیسی مقاله Splenic neoplasms,Sclerosing angiomatoid nodular transformation,Pediatric spleen lesion,Case Report
نویسندگان مقاله Farzaneh Ramezani |
Department of Pathology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran

Sare Kamali |
Department of Pathology, Faculty of Medicine, Hormozgan University of Medical Sciences, Bandar Abbas, Iran

Ramin Mashoufi |
Department of Radiology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran

Seyed Ali Ebrahimi |
Department of Medical Sciences, Islamic Azad University, Mashhad, Iran.

Maryam Soltan |
Department of Pathology, Faculty of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran

نشانی اینترنتی https://ijp.iranpath.org/article_722982_c4058dafdcc66fc0d402dd9f90de7fce.pdf
فایل مقاله فایلی برای مقاله ذخیره نشده است
کد مقاله (doi)
زبان مقاله منتشر شده en
موضوعات مقاله منتشر شده
نوع مقاله منتشر شده
برگشت به: صفحه اول پایگاه   |   نسخه مرتبط   |   نشریه مرتبط   |   فهرست نشریات