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Middle East Journal of Digestive Diseases، جلد ۱۷، شماره ۲، صفحات ۸۳-۸۷
عنوان فارسی
چکیده فارسی مقاله
کلیدواژه‌های فارسی مقاله
عنوان انگلیسی The endoscopic ultrasonography (EUS) and fine needle aspiration (FNA) agreement in patients with pancreatic cystic lesions, Tehran, Iran.
چکیده انگلیسی مقاله Introduction and Purpose: The purpose of this study is to investigate the concordance of endoscopic ultrasonography (EUS) results and biochemical analysis of cyst fluid obtained through fine needle aspiration (FNA) in diagnosing mucinous pancreatic cysts. Methods: In this retrospective study, the medical records of 81 patients with pancreatic cystic lesions were examined. EUS results and cyst fluid analysis (carcinoembryonic antigen (CEA) and amylase) concordance rate was evaluated and the agreement of the two methods was assessed through Cohen's kappa coefficient. Results: The concordance rate of EUS and cyst fluid analysis with CEA cutoff point >192 ng/mL was 52.5% and 69.2%, respectively for MCN and IPMN diagnosis. The sensitivity and specificity of cyst fluid analysis for MCN and IPMN (taking EUS as the reference) were 59.1% and 93.33%, respectively. The positive predictive value was equal to 97.5% and its negative predictive value was 34.14. Using the CEA <5 ng/ml cut-off point for detecting SCN cysts was associated with the sensitivity, specificity, positive and negative predictive value of 73.3%, 78.8%, 44% and 92.8% respectively. The concordance rate of EUS and pancreatic cyst fluid analysis was 65.43%, with the Kappa correlation coefficient of 0.326. Conclusion: The specificity and positive predictive value of CEA>192 for the diagnosis of mucinous pancreatic cysts is high but it is associated with a moderate sensitivity and a low negative predictive value. Altogether, there is a moderate agreement between the results of EUS and biochemical analysis of FNA cyst fluid in diagnosing mucinous pancreatic cysts.
کلیدواژه‌های انگلیسی مقاله Cystic pancreatic lesions, endoscopic ultrasound, cyst fluid analysis
نویسندگان مقاله | Arman Rahimi


| Elham Sobh Rakhshankhah


| Farhad Zamani


| Mahmoodrza Khoonsari


| Amirhossein Faraji


| Mehdi Nikkhah


| Gholam Reza Hemmasi


| Hossein Ajdarkosh


نشانی اینترنتی http://mejdd.org/index.php/mejdd/article/view/3093
فایل مقاله فایلی برای مقاله ذخیره نشده است
کد مقاله (doi) 10.15171/middle east j di.v17i2.3093
زبان مقاله منتشر شده en
موضوعات مقاله منتشر شده
نوع مقاله منتشر شده Original Article
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