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Journal of Reproduction and Infertility، جلد ۲۶، شماره ۱، صفحات ۵۸-۶۴

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عنوان انگلیسی Severe Immune Thrombocytopenic Purpura in a Patient at 33 Weeks of Gestation: A Case Report
چکیده انگلیسی مقاله

Background: Immune thrombocytopenia (ITP) is an autoimmune condition that affects individuals of all ages, leading to a heightened risk of bleeding. ITP accounts for 5% of all pregnancy-related thrombocytopenia cases with an incidence of 1 in every 1,000 pregnant women. Several conditions can cause thrombocytopenia during pregnancy, making the diagnosis challenging. Current treatment of patients with ITP focuses on maintaining a safe platelet count rather than correcting it to normal levels. 
Case Presentation: This article presents a case of a 26-year-old patient at 33 weeks of gestation with severe symptoms of thrombocytopenia, evidenced by a platelet count of 1000/mm3. The patient experienced self-resolving episodes of gingival bleeding, vaginal bleeding, and petechiae on her abdomen, as well as on both upper and lower extremities, over a duration of three days. She was successfully managed with prednisolone and intravenous immunoglobulin (IVIG), resulting in favorable maternal and neonatal outcomes.
Conclusion: While there are currently no universally accepted guidelines for the treatment of ITP, expert consensus recommendations are available. Therefore, treatment should be individualized and closely monitored. A multidisciplinary team approach is essential for the effective management of ITP during pregnancy.

کلیدواژه‌های انگلیسی مقاله Bleeding, Immune thrombocytopenia, Immunoglobulins, Platelet count, Prednisolone, Pregnancy, Purpura

نویسندگان مقاله | Rawad Halimeh
The Centre for Reproductive and Genetic Health (CRGH), London, UK


| Joseph Klim
Faculty of Medicine and Medical Sciences, University of Balamand, El-Koura, Lebanon


| Lea Aoude
Faculty of Medicine and Medical Sciences, University of Balamand, El-Koura, Lebanon


| Marianne Bersaoui
Department of Obstetrics and Gynecology, Saint George Hospital University Medical Center, Beirut, Lebanon


| Bernard Najib
Centre Antoine Lacassagne, Nice, France


| Saab Wiam
Department of Obstetrics and Gynecology, American University of Beirut Medical Center, Beirut, Lebanon


| Fadi Fakhoury
Department of Anesthesia, Montreuil Intercommunal Hospital Center, Montreuil, France


| Rana Skaf
Department of Obstetrics and Gynecology, Saint George Hospital University Medical Center, Beirut, Lebanon



نشانی اینترنتی https://www.jri.ir/article/140261
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