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Iranian Journal of Psychiatry، جلد ۲، شماره ۳، صفحات ۱۲۴-۱۲۶

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عنوان انگلیسی Evaluating the Effect of 8-Week Treatment With Risperidone On Fasting Blood Glucose of Patients with Schizophrenia
چکیده انگلیسی مقاله Objective : This study was designed to evaluate the effects of risperidone on fasting blood glucose (FBG) in patients with Schizophrenia . Method: Seventy five non-diabetic patients with Schizophrenia (based on Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition criteria) entered this cross-sectional study. Patients did not receive any medications (Including risperidone) affecting serum FBG levels for at least 2 weeks prior to the initiation of the study. Patients received the mean dose of 4.5mg (range 2-12mg) risperidone for 8 weeks. Pregnant women, patients with diabetes mellitus and a history of any major heart disease were excluded from this study.Additionally, none of the patients should have received electroconvulsive therapy within 6 months prior to the initiation of the antiphsychotics.FBG levels were measured at the initiation and 8 weeks after starting risperidone. Results: Fifty one patients completed the study. The mean FBG level was increased from 88.9mg/dL (baseline) to 94.4 mg/dL at week 8 (P =0.003). This 8-week study showed that FBG levels may increase in schizophrenic patients receiving risperidone. Conclusion: Measuring and monitoring FBG before the initiation and during the treatment with risperidone is suggested.
کلیدواژه‌های انگلیسی مقاله Blood glucose,Risperidone,Schizophrenia

نویسندگان مقاله فیروزه رییسی | firouzeh raisi
department of psychiatry, tehran university of medical sciences, tehran, iran psychiatry amp;amp; psychology research center, tehran university of medical sciences, tehran, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)

هادی اخوت | hadi okhovatpoor
department of clinical pharmacy, school of pharmacy, tehran university of medical sciences, tehran, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)

سیمین دشتی خویدکی | simin dashti khavidaki
department of clinical pharmacy, school of pharmacy, tehran university of medical sciences, tehran, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)

حسین خلیلی | hossein khalili
department of clinical pharmacy, school of pharmacy, tehran university of medical sciences, tehran, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)

پدیده قایلی | padideh ghaeli
department of psychiatry, tehran university of medical sciences, tehran, iran psychiatry amp;amp; psychology research center, tehran university of medical sciences, tehran, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)


نشانی اینترنتی http://ijps.tums.ac.ir/index.php/ijps/article/view/450
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